Structure of PDB 7tuc Chain A Binding Site BS01
Receptor Information
>7tuc Chain A (length=274) Species:
9606
(Homo sapiens) [
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GSHSMRYFYTAMSRPGRGEPRFITVGYVDDTLFVRFDSDATSPRKEPRAP
WIEQEGPEYWDRETQISKTNTQCYRENLRTALRYYNQSEAGSHIIQRMYG
CDVGPDGRLLRGYDQYAYDGKDYIALNEDLSSWTAADTAAQITQRKWEAA
RVAEQDRAYLEGLCVESLRRYLENGKETLQRADPPKTHVTHHPISDHEVT
LRCWALGFYPAEITLTWQRDGEDQTQDTELVETRPAGDRTFQKWAAVVVP
SGEEQRYTCHVQHEGLPKPLTLRW
Ligand information
>7tuc Chain P (length=9) Species:
32630
(synthetic construct) [
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EEFGRAFSF
Receptor-Ligand Complex Structure
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PDB
7tuc
Structural mechanism of tapasin-mediated MHC-I peptide loading in antigen presentation.
Resolution
1.25 Å
Binding residue
(original residue number in PDB)
Y7 Y9 K45 E63 I66 N77 Y84 Y99 Y123 T143 K146 W147 V152 Q155 D156 Y159 L163 S167 R170 Y171
Binding residue
(residue number reindexed from 1)
Y7 Y9 K45 E63 I66 N77 Y84 Y99 Y123 T143 K146 W147 V152 Q155 D156 Y159 L163 S167 R170 Y171
Enzymatic activity
Enzyme Commision number
?
External links
PDB
RCSB:7tuc
,
PDBe:7tuc
,
PDBj:7tuc
PDBsum
7tuc
PubMed
36115831
UniProt
D5H3J5
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