Structure of PDB 7trl Chain A Binding Site BS01
Receptor Information
>7trl Chain A (length=90) Species:
9606
(Homo sapiens) [
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SPEFISNLSMQTHAARMRTFMYWPSSVPVQPEQLASAGFYYVGRNDDVKC
FCCDGGLRCWESGDDPWVEHAKWFPRCEFLIRMKGQEFVD
Ligand information
>7trl Chain B (length=4) Species:
9606
(Homo sapiens) [
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ARTK
Receptor-Ligand Complex Structure
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PDB
7trl
Molecular basis for nuclear accumulation and targeting of the inhibitor of apoptosis BIRC2.
Resolution
1.74 Å
Binding residue
(original residue number in PDB)
G312 L313 R314 C315 W316 W329
Binding residue
(residue number reindexed from 1)
G56 L57 R58 C59 W60 W73
Enzymatic activity
Enzyme Commision number
2.3.2.27
: RING-type E3 ubiquitin transferase.
External links
PDB
RCSB:7trl
,
PDBe:7trl
,
PDBj:7trl
PDBsum
7trl
PubMed
37524969
UniProt
Q13490
|BIRC2_HUMAN Baculoviral IAP repeat-containing protein 2 (Gene Name=BIRC2)
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