Structure of PDB 7tr4 Chain A Binding Site BS01
Receptor Information
>7tr4 Chain A (length=275) Species:
9606
(Homo sapiens) [
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GSHSMRYFFTSVSRPGRGEPRFIAVGYVDDTQFVRFDSDAASQRMEPRAP
WIEQEGPEYWDGETRKVKAHSQTHRVDLGTLRGYYNQSEAGSHTVQRMYG
CDVGSDWRFLRGYHQYAYDGKDYIALKEDLRSWTAADMAAQTTKHKWEAA
HVAEQLRAYLEGTCVEWLRRYLENGKETLQRTDAPKTHMTHHAVSDHEAT
LRCWALSFYPAEITLTWQRDGEDQTQDTELVETRPAGDGTFQKWAAVVVP
SGQEQRYTCHVQHEGLPKPLTLRWE
Ligand information
>7tr4 Chain P (length=10) Species:
9606
(Homo sapiens) [
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ELAGIGILTV
Receptor-Ligand Complex Structure
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PDB
7tr4
Facile repurposing of peptide-MHC-restricted antibodies for cancer immunotherapy.
Resolution
2.3 Å
Binding residue
(original residue number in PDB)
Y7 E63 K66 V67 H70 T73 D77 R97 Y99 Y116 T143 K146 W147 V152 Q155 Y159 T163 W167 Y171
Binding residue
(residue number reindexed from 1)
Y7 E63 K66 V67 H70 T73 D77 R97 Y99 Y116 T143 K146 W147 V152 Q155 Y159 T163 W167 Y171
Enzymatic activity
Enzyme Commision number
?
External links
PDB
RCSB:7tr4
,
PDBe:7tr4
,
PDBj:7tr4
PDBsum
7tr4
PubMed
36593402
UniProt
A0A140T9X5
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