Structure of PDB 7to8 Chain A Binding Site BS01
Receptor Information
>7to8 Chain A (length=116) Species:
9606
(Homo sapiens) [
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PGRKTNQLQYMQNVVVKTLWKHQFAWPFYQPVDAIKLNLPDYHKIIKNPM
DMGTIKKRLENNYYWSASECMQDFNTMFTNCYIYNKPTDDIVLMAQALEK
IFLQKVAQMPQEEVEL
Ligand information
>7to8 Chain C (length=13) Species:
32630
(synthetic construct) [
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QRSLKLLKHLYHG
Receptor-Ligand Complex Structure
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PDB
7to8
BRD3-BD1 in complex with RaPID linear peptide 2xAcK.1 (diAcK)
Resolution
1.5 Å
Binding residue
(original residue number in PDB)
W57 P58 Q61 K67 L68 N69 I122
Binding residue
(residue number reindexed from 1)
W26 P27 Q30 K36 L37 N38 I91
Enzymatic activity
Enzyme Commision number
?
External links
PDB
RCSB:7to8
,
PDBe:7to8
,
PDBj:7to8
PDBsum
7to8
PubMed
37992806
UniProt
Q15059
|BRD3_HUMAN Bromodomain-containing protein 3 (Gene Name=BRD3)
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