Structure of PDB 7t80 Chain A Binding Site BS01

Receptor Information
>7t80 Chain A (length=216) Species: 10090 (Mus musculus) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
NDPVLLNLPMNVTISENSPVSSFVAHVLASDADSGCNALLTFNITAGNRE
RAFFINATTGIVTVNRPLDRERIPEYRLTVSVKDNPENPRIARKDFDLLL
VSLADENDNHPLFTEGTYQAEVMENSPAGTPLTVLNGPILALDADEDVYA
VVTYQLLGTHSDLFVIDNSTGVVTVRSGIIIDREAFSPPFLELLLLAEDI
GQLNGTAHLFITILDD
Ligand information
Ligand IDCA
InChIInChI=1S/Ca/q+2
InChIKeyBHPQYMZQTOCNFJ-UHFFFAOYSA-N
SMILES
SoftwareSMILES
CACTVS 3.341[Ca++]
ACDLabs 10.04
OpenEye OEToolkits 1.5.0		[Ca+2]
FormulaCa
NameCALCIUM ION
ChEMBL
DrugBankDB14577
ZINC
PDB chain7t80 Chain A Residue 2101 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
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PDB7t80 Crystal Structure of Mouse Cadherin-23 EC18-19
Resolution2.301 Å
Binding residue
(original residue number in PDB)		E1839 E1894 D1928 E1929 D1931 D1968
Binding residue
(residue number reindexed from 1)		E16 E71 D105 E106 D108 D145
Annotation score4
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0005509 calcium ion binding
Biological Process
GO:0007155 cell adhesion
GO:0007156 homophilic cell adhesion via plasma membrane adhesion molecules
Cellular Component
GO:0005886 plasma membrane
GO:0016020 membrane

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:7t80, PDBe:7t80, PDBj:7t80
PDBsum7t80
PubMed
UniProtQ99PF4|CAD23_MOUSE Cadherin-23 (Gene Name=Cdh23)

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