Structure of PDB 7t7t Chain A Binding Site BS01

Receptor Information
>7t7t Chain A (length=466) Species: 55188 (Citrus unshiu) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
MGRDEMQMSEAKRAYRSAKEEGNRQEEARWANVIGDILKNRGEYVEALKW
FRIDYDVSVKYLPEKHLLPTCQSLGEVYLRLEHFKDALIYQKKHLELAKD
ASDLVEQQRACTQLGRTYYEMFLRYSIRNAKKYFKSAMKLAQTLKSSFLK
EYIDAHNNIGMLQMEDNLEEAKKLLIRGLEICNEEDDDGRSRLHHNLGNV
YMELRMWDKSREHIEQDIIICKKIEHRQGEAKGYINLGELHYRVQKYDEA
ILCYQKALNLAQSMEDEDALASQIDQNIETVKKAIEVMDELKKEEQNLKK
LTRNMIIAKGTSQERKSLLQQNASLDCLIEKSSMIFAWLKHCEYAKRKKR
IASELCDKGKLSDSFLVIGESYQKLRKFNKAIKWYTKSWEMYKSIGNLEG
QALAKVNMGNVLDSNGDWAGALDAFQEGYRIAVEANLPSVQLSALENMHY
SHMIRFDNIEEARRLQ
Ligand information
>7t7t Chain W (length=28) Species: 3702 (Arabidopsis thaliana) [Search peptide sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
KQTARKQLATKAARKSAPATGGVKKPHR
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB7t7t The histone H3.1 variant regulates TONSOKU-mediated DNA repair during replication.
Resolution3.17 Å
Binding residue
(original residue number in PDB)		E26 R29 W30 N32 V33 D54 H66 P69 T70 Q72 S73 R109 Q113 R116 Y119 E163 N170 M173 R209 H212 N216 D234 K249 N253 E256 Y259 Q293 N294 T297 S350 M351 F353 N424 N427 D430 E463 N464
Binding residue
(residue number reindexed from 1)		E26 R29 W30 N32 V33 D54 H66 P69 T70 Q72 S73 R109 Q113 R116 Y119 E151 N158 M161 R192 H195 N199 D217 K232 N236 E239 Y242 Q276 N277 T280 S333 M334 F336 N407 N410 D413 E446 N447
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Biological Process
GO:0006325 chromatin organization
GO:0009933 meristem structural organization
GO:0040029 epigenetic regulation of gene expression
GO:0072423 response to DNA damage checkpoint signaling
Cellular Component
GO:0005634 nucleus

View graph for
Biological Process
View graph for
Cellular Component
External links
PDB RCSB:7t7t, PDBe:7t7t, PDBj:7t7t
PDBsum7t7t
PubMed35298257
UniProtA0A2H5Q1B8|TONSL_CITUN Protein TONSOKU (Gene Name=TSK)

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