Structure of PDB 7t6i Chain A Binding Site BS01

Receptor Information
>7t6i Chain A (length=183) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
IKADHVSTYAAFVQTHRPTGEFMFEFDEDEQFYVDLDKKETVWHLEEFGR
AFSFEAQGGLANIAILNNNLNTLIQRSNHTQAANDPPEVTVFPKEPVELG
QPNTLICHIDRFFPPVLNVTWLCNGEPVTEGVAESLFLPRTDYSFHKFHY
LTFVPSAEDVYDCRVEHWGLDQPLLKHWEATSG
Ligand information
>7t6i Chain C (length=16) Species: 10360 (Human herpesvirus 5 strain AD169) [Search peptide sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
PVADAVIHASGKQMWQ
Receptor-Ligand Complex Structure
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PDB7t6i Human T cells recognize HLA-DP-bound peptides in two orientations.
Resolution2.3 Å
Binding residue
(original residue number in PDB)		Y9 Q31 R50 A51 F52 S53 F54 N62 I65 N68 N69 T72 R76
Binding residue
(residue number reindexed from 1)		Y9 Q31 R50 A51 F52 S53 F54 N62 I65 N68 N69 T72 R76
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Biological Process
GO:0006955 immune response
GO:0019882 antigen processing and presentation
Cellular Component
GO:0016020 membrane
GO:0042613 MHC class II protein complex

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Biological Process
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Cellular Component
External links
PDB RCSB:7t6i, PDBe:7t6i, PDBj:7t6i
PDBsum7t6i
PubMed36442096
UniProtQ95HB9

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