Structure of PDB 7t2x Chain A Binding Site BS01
Receptor Information
>7t2x Chain A (length=210) Species:
9606
(Homo sapiens) [
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LTADQMVSALLDAEPPILYSEASMMGLLTNLADRELVHMINWAKRVPGFV
DLTLHDQVHLLECAWLEILMIGLVWRSMEHPGKLLFAPNLLLDRNQGMVE
IFDMLLATSSRFRMMNLQGEEFVCLKSIILLNSGVYTLEEKDHIHRVLDK
ITDTLIHLMAKAGLTLQQQHQRLAQLLLILSHIRHMSNKGMEHLYSMKLS
DLLLEMLDAH
Ligand information
>7t2x Chain C (length=8) Species:
9606
(Homo sapiens) [
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KILHRLLQ
Receptor-Ligand Complex Structure
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PDB
7t2x
A New Chemotype of Chemically Tractable Nonsteroidal Estrogens Based on a Thieno[2,3- d ]pyrimidine Core.
Resolution
2.6 Å
Binding residue
(original residue number in PDB)
I358 V376 L539 M543
Binding residue
(residue number reindexed from 1)
I40 V58 L202 M206
Enzymatic activity
Enzyme Commision number
?
External links
PDB
RCSB:7t2x
,
PDBe:7t2x
,
PDBj:7t2x
PDBsum
7t2x
PubMed
35859859
UniProt
P03372
|ESR1_HUMAN Estrogen receptor (Gene Name=ESR1)
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