Structure of PDB 7t1u Chain A Binding Site BS01
Receptor Information
>7t1u Chain A (length=105) Species:
9606
(Homo sapiens) [
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APWQAEEWYFGKITRRESERLLLNAENPRGTFLVREGQSQPDYVLSVSDF
DNAKGLNVKHYIIRKLDSGFYITSRTQFNSLQQLVAYYSKHADGLCHRLT
TVCPT
Ligand information
>7t1u Chain D (length=7) Species:
32630
(synthetic construct) [
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EPQYEEI
Receptor-Ligand Complex Structure
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PDB
7t1u
Engineered SH2 Domains for Targeted Phosphoproteomics.
Resolution
2.65 Å
Binding residue
(original residue number in PDB)
R158 R178 S182 Q183 K202 H203 Y204 I205 I216 T217 G238
Binding residue
(residue number reindexed from 1)
R15 R35 S39 Q40 K59 H60 Y61 I62 I72 T73 G94
Enzymatic activity
Enzyme Commision number
2.7.10.2
: non-specific protein-tyrosine kinase.
External links
PDB
RCSB:7t1u
,
PDBe:7t1u
,
PDBj:7t1u
PDBsum
7t1u
PubMed
35613471
UniProt
P12931
|SRC_HUMAN Proto-oncogene tyrosine-protein kinase Src (Gene Name=SRC)
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