Structure of PDB 7t1l Chain A Binding Site BS01

Receptor Information
>7t1l Chain A (length=99) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
KPLHEQLWYHGAIPRAEVAELLVHSGDFLVRESETVKGAYALSVLWDGLP
RHFLIQSLDNLYRLEGEGFPSIPLLIDHLLSTQQPLTKKSGVVLHRAVP
Ligand information
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB7t1l Engineered SH2 Domains for Targeted Phosphoproteomics.
Resolution1.35 Å
Binding residue
(original residue number in PDB)
R16 R32 S34 E35 T36 R52 H53 F54 Q57
Binding residue
(residue number reindexed from 1)
R15 R31 S33 E34 T35 R51 H52 F53 Q56
Enzymatic activity
Enzyme Commision number 2.7.10.2: non-specific protein-tyrosine kinase.
External links
PDB RCSB:7t1l, PDBe:7t1l, PDBj:7t1l
PDBsum7t1l
PubMed35613471
UniProtP07332|FES_HUMAN Tyrosine-protein kinase Fes/Fps (Gene Name=FES)

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