Structure of PDB 7swq Chain A Binding Site BS01

Receptor Information
>7swq Chain A (length=791) Species: 3702 (Arabidopsis thaliana) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
SNFAPRPGFGTLGTKCIVKANHFLADLPTKDLNQYDVTITPEVSSKSVNR
AIIAELVRLYKESDLGRRLPAYDGRKSLYTAGELPFTWKEFSVKIVDERS
YKVAIKFVARANMHHLGEFLCPQEAVQILDIVLRELSVKRFCPVGRSFFS
PDIKTPQRLGEGLESWCGFYQSIRPTQMGLSLNIDMASAAFIEPLPVIEF
VAQLLGKDVLSKPLSDSDRVKIKKGLRGVKVEVTHRANVRRKYRVAGLTT
QPTREIQHTHLPCLQVGNQKKASYLPMEACKIVEGQRYTKRLNEKQITAL
LKVTCQRPRDRENDILRTVQHNAYDQDPYAKEFGMNISEKLASVEARILP
APWLKYHENGKEKDCLPQVGQWNMMNKKMINGMTVSRWACVNFSRSVQEN
VARGFCNELGQMCEVSGMEFNPEPVIPIYSARPDQVEKALKHVYHTSMNK
TKGKELELLLAILPDNNGSLYGDLKRICETELGLISQCCLTKHVFKISKQ
YLANVSLKINVKMGGRNTVLVDAISCRIPLVSDIPTIIFGADVTHPSPSI
AAVVASQDWPEVTKYAGLVCAQAHRQELIQDLYKTWQDPVRGTVSGGMIR
DLLISFRKATGQKPLRIIFYRAGVSEGQFYQVLLYELDAIRKACASLEPN
YQPPVTFIVVQKRHHTRLFANNHRDKNSTDRSGNILPGTVVDTKICHPTE
FDFYLCSHAGIQGTSRPAHYHVLWDENNFTADGIQSLTNNLCYTYARCTR
SVSIVPPAYYAHLAAFRARFYLEVKPLPALKENVKRVMFYC
Ligand information
>7swq Chain B (length=21) [Search RNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
uggagugugacaaugguguuu
.....................
Receptor-Ligand Complex Structure
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PDB7swq Structural basis for RNA slicing by a plant Argonaute.
Resolution3.79 Å
Binding residue
(original residue number in PDB)		D222 K366 R378 R383 Y385 N435 K438 S440 Y441 R458 T471 C472 N634 Y638 K642 Q654 C655 L657 H660 Y668 N671 K675 K835 R840 H881 I884 T887 R889 R920 C921 R923 S926 Y932
Binding residue
(residue number reindexed from 1)		D97 K224 R236 R241 Y243 N268 K271 S273 Y274 R291 T304 C305 N467 Y471 K475 Q487 C488 L490 H493 Y501 N504 K508 K662 R667 H708 I711 T714 R716 R747 C748 R750 S753 Y759
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0003676 nucleic acid binding
GO:0003723 RNA binding
GO:0005515 protein binding
GO:0035198 miRNA binding
Biological Process
GO:0006417 regulation of translation
GO:0009934 regulation of meristem structural organization
GO:0010072 primary shoot apical meristem specification
GO:0010586 miRNA metabolic process
GO:0031047 regulatory ncRNA-mediated gene silencing
GO:0035019 somatic stem cell population maintenance
GO:0051607 defense response to virus
GO:1902183 regulation of shoot apical meristem development
Cellular Component
GO:0005737 cytoplasm
GO:0009536 plastid
GO:1990904 ribonucleoprotein complex

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Molecular Function
View graph for
Biological Process
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Cellular Component
External links
PDB RCSB:7swq, PDBe:7swq, PDBj:7swq
PDBsum7swq
PubMed37127820
UniProtQ9XGW1|AGO10_ARATH Protein argonaute 10 (Gene Name=AGO10)

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