Structure of PDB 7snq Chain A Binding Site BS01

Receptor Information
>7snq Chain A (length=209) Species: 11678 (Human immunodeficiency virus type 1 BH10) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
PIVQNLQGQMVHQCISPRTLNAWVKVVEEKAFSPEVIPMFSALSCGATPQ
DLNTMLNTVGGHQAAMQMLKETINEEAAEWDRLHPREPRGSDIAGTTSTL
QEQIGWMTHNPPIPVGEIYKRWIILGLNKIVRMYSPTSILDIRQGPKEPF
RDYVDRFYKTLRAEQASQEVKNAATETLLVQNANPDCKTILKALGPGATL
EEMMTACQG
Ligand information
>7snq Chain M (length=14) Species: 11676 (Human immunodeficiency virus 1) [Search peptide sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
PVLFPGQPFGQPPL
Receptor-Ligand Complex Structure
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PDB7snq Prion-like low complexity regions enable avid virus-host interactions during HIV-1 infection.
Resolution2.81 Å
Binding residue
(original residue number in PDB)		N53 L56 N57 K70 N74 S102 G106 T107
Binding residue
(residue number reindexed from 1)		N53 L56 N57 K70 N74 S91 G95 T96
Enzymatic activity
Enzyme Commision number 2.7.7.-
2.7.7.49: RNA-directed DNA polymerase.
2.7.7.7: DNA-directed DNA polymerase.
3.1.-.-
3.1.13.2: exoribonuclease H.
3.1.26.13: retroviral ribonuclease H.
3.4.23.16: HIV-1 retropepsin.
Gene Ontology

View graph for
Biological Process
External links
PDB RCSB:7snq, PDBe:7snq, PDBj:7snq
PDBsum7snq
PubMed36202818
UniProtP03366|POL_HV1B1 Gag-Pol polyprotein (Gene Name=gag-pol)

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