Structure of PDB 7skq Chain A Binding Site BS01

Receptor Information
>7skq Chain A (length=313) Species: 347537 (Bat SARS CoV Rf1/2004) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
VKTIKVFTTVDNTNLHTQLVDMSMTYGQHFGPTYLDGADVTKVKPHVNHE
GKTFFVLPSDDTLRSEAFEYYHTLDESFLGRYMSALNHTKKWKFPQVGGL
TSIKWADNNCYLSSVLLALQQIEVKFNAPALQEAYYRARAGDAANFCALI
LAYSNKTVGELGDVRETMTHLLQHANLESAKRVLNLVCKHCGQKTTTLMG
VEAVMYMGTLSYDELKAGVSIPCVCGRDATQYLVQQESSFVMMSAPPAEY
KLQQGTFLCANEYTGNYQCGHYTHITAKETLYRIDGAHLTKMSEYKGPVT
DVFYKETSYTTTI
Ligand information
Ligand IDZN
InChIInChI=1S/Zn/q+2
InChIKeyPTFCDOFLOPIGGS-UHFFFAOYSA-N
SMILES
SoftwareSMILES
CACTVS 3.341[Zn++]
ACDLabs 10.04
OpenEye OEToolkits 1.5.0		[Zn+2]
FormulaZn
NameZINC ION
ChEMBLCHEMBL1236970
DrugBankDB14532
ZINC
PDB chain7skq Chain A Residue 401 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
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PDB7skq Exploring Noncovalent Protease Inhibitors for the Treatment of Severe Acute Respiratory Syndrome and Severe Acute Respiratory Syndrome-Like Coronaviruses.
Resolution3.16 Å
Binding residue
(original residue number in PDB)		C190 C193 C225 C227
Binding residue
(residue number reindexed from 1)		C188 C191 C223 C225
Annotation score4
Enzymatic activity
Enzyme Commision number 3.4.19.12: ubiquitinyl hydrolase 1.
Gene Ontology
Molecular Function
GO:0008234 cysteine-type peptidase activity
Biological Process
GO:0006508 proteolysis

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Molecular Function
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Biological Process
External links
PDB RCSB:7skq, PDBe:7skq, PDBj:7skq
PDBsum7skq
PubMed35199517
UniProtQ0QDZ2

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