Structure of PDB 7sjr Chain A Binding Site BS01

Receptor Information
>7sjr Chain A (length=911) Species: 1772 (Mycolicibacterium smegmatis) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
LLEPGSNGVVRLLGGPGTGKSSLLVDTAVQHDPESVLLLTGSARLRTAAR
AAITARLGVVREPLVRTVHSYAFAVLRLAAQTSAEQDGIIRELLAGDLED
GWPEQLWPALTTAGFATELRDLMARCTERGVDPIALQRLGRTAKRPEWLA
AGRFAQAYEQIMLAAELVGAALEALGADDELLDTERNRIKLLLVDDAQHL
DPQAARLVRALAAGTGLTVIAGDPDQSVFVLLRDDTHPAITLTQSYRCAP
EIASAITGLGQRLTRHWTGNPQREGTVTVRLAASTHAEGTMIADALRRAH
LVDGIPWSQMAVIVRSVPGTALARALTAAGVPVQDVPVGRQPAAAALLTV
LDVTATGHLDADSAVALLTGPIGRVDPVTLRQLRRALRRADGSQPPRDFG
DLLVDAIEREPKGLSAEHARTLRRLRAVLTAARRSDARYTLWQAWHASGL
QRRWLAASERVGAQADRDLDAVTTLFDVADQYVNRLRGLVDHVTRAEAVA
VLSVHGALAGEWDFVVIAGVQEGLWPNMIPRGGVLGTQHLVDVLDGVADM
TDRTVSTRAPLVAEERRLLMAAMGRARTRVMITAVDSDTGLLPSPFCAEI
SAWATEPPLVAPRVLAPSALVGRLRAVVCAPAVDDDARACAAAQLARLAA
AGVPGADPSQWHAMTSLTTEEPLWSEHVVTLSPSTLQMLTDCPLRWLLER
HGGDDGRDVRSTVGSLVHALVSEPTESQLVNELEKVWDDLPYDAKWYSDN
ELARHRAMLETFTRWREDTRRQLTEVATEIPVEGIVVEPPGVRVRGRLDR
LERDEAGRLVVVDLKTGKSPVTKDDAQNHAQLAMYQLAVAAGLLDDEPGG
GKLVYLGKATEREQDPLTPDKRAEWLETVGEAAAATAGPRFVARVNNGCA
NCPVRSSCPAQ
Ligand information
Receptor-Ligand Complex Structure
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PDB7sjr Structure-activity relationships at a nucleobase-stacking tryptophan required for chemomechanical coupling in the DNA resecting motor-nuclease AdnAB.
Resolution3.8 Å
Binding residue
(original residue number in PDB)		R825 S826 K936 G938 K939 S940 K944 R990
Binding residue
(residue number reindexed from 1)		R710 S711 K815 G817 K818 S819 K823 R862
Enzymatic activity
Enzyme Commision number 5.6.2.4: DNA 3'-5' helicase.
Gene Ontology
Molecular Function
GO:0003677 DNA binding
GO:0003678 DNA helicase activity
GO:0004386 helicase activity
GO:0004527 exonuclease activity
GO:0005524 ATP binding
GO:0016787 hydrolase activity
GO:0016853 isomerase activity
GO:0043138 3'-5' DNA helicase activity
Biological Process
GO:0000725 recombinational repair
GO:0006281 DNA repair
GO:0032508 DNA duplex unwinding
Cellular Component
GO:0005829 cytosol
GO:0033202 DNA helicase complex

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:7sjr, PDBe:7sjr, PDBj:7sjr
PDBsum7sjr
PubMed34967418
UniProtA0QTR9

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