Structure of PDB 7sg0 Chain A Binding Site BS01

Receptor Information
>7sg0 Chain A (length=180) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
IVADHVASYGVNLYQSYGPSGQYTHEFDGDEQFYVDLGRKETVWCLPVLR
QFRFDPQFALTNIAVLKHNLNSLIKRSNSTAATNEVPEVTVFSKSPVTLG
QPNILICLVDNIFPPVVNITWLSNGHSVTEGVSETSFLSKSDHSFFKISY
LTLLPSAEESYDCKVEHWGLDKPLLKHWEP
Ligand information
Receptor-Ligand Complex Structure
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PDB7sg0 W316 TCR in complex with HLA-DQ2-omega1
Resolution3.0 Å
Binding residue
(original residue number in PDB)
F51 R52 F54 F58 N62 N69 L73
Binding residue
(residue number reindexed from 1)
F52 R53 F54 F58 N62 N69 L73
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Biological Process
GO:0006955 immune response
GO:0019882 antigen processing and presentation
Cellular Component
GO:0016020 membrane
GO:0042613 MHC class II protein complex

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Biological Process

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Cellular Component
External links
PDB RCSB:7sg0, PDBe:7sg0, PDBj:7sg0
PDBsum7sg0
PubMed35065967
UniProtP01909|DQA1_HUMAN HLA class II histocompatibility antigen, DQ alpha 1 chain (Gene Name=HLA-DQA1)

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