Structure of PDB 7rtd Chain A Binding Site BS01

Receptor Information
>7rtd Chain A (length=274) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
GSHSMRYFFTSVSRPGRGEPRFIAVGYVDDTQFVRFDSDAASQRMEPRAP
WIEQEGPEYWDGETRKVKAHSQTHRVDLGTLRGYYNQSEAGSHTVQRMYG
CDVGSDWRFLRGYHQYAYDGKDYIALKEDLRSWTAADMAAQTTKHKWEAA
HVAEQLRAYLEGTCVEWLRRYLENGKETLQRTDAPKTHMTHHAVSDHEAT
LRCWALSFYPAEITLTWQRDGEDQTQDTELVETRPAGDGTFQKWAAVVVP
SGQEQRYTCHVQHEGLPKPLTLRW
Ligand information
>7rtd Chain C (length=9) Species: 2697049 (Severe acute respiratory syndrome coronavirus 2) [Search peptide sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
YLQPRTFLL
Receptor-Ligand Complex Structure
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PDB7rtd Molecular Basis of a Dominant SARS-CoV-2 Spike-Derived Epitope Presented by HLA-A*02:01 Recognised by a Public TCR.
Resolution2.05 Å
Binding residue
(original residue number in PDB)
Y7 F9 E63 K66 V67 H70 T73 V76 D77 L81 Y84 Y99 H114 Y116 T143 K146 W147 V152 Q155 L156 Y159 T163 W167 Y171
Binding residue
(residue number reindexed from 1)
Y7 F9 E63 K66 V67 H70 T73 V76 D77 L81 Y84 Y99 H114 Y116 T143 K146 W147 V152 Q155 L156 Y159 T163 W167 Y171
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Biological Process
GO:0006955 immune response
GO:0019882 antigen processing and presentation

View graph for
Biological Process
External links
PDB RCSB:7rtd, PDBe:7rtd, PDBj:7rtd
PDBsum7rtd
PubMed34685626
UniProtQ53Z42

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