Structure of PDB 7rrg Chain A Binding Site BS01
Receptor Information
>7rrg Chain A (length=272) Species:
9606
(Homo sapiens) [
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GSHSMRYFFTSVSRPGRGEPRFIAVGYVDDTQFVRFDSDAASQRMEPRAP
WIEQEGPEYWDQETRNVKAQSQTDRVDLGTLRGYYNQSEAGSHTIQIMYG
CDVGSDGRFLRGYRQDAYDGKDYIALNEDLRSWTAADMAAQITKRKWEAA
HEAEQLRAYLDGTCVEWLRRYLENGKETLQRTDPPKTHMTHHPSDHEATL
RCWALGFYPAEITLTWQRDGEDQTQTELVETRPAGDGTFQKWAAVVVPSG
EEQRYTCHVQHEGLPKPLTLRW
Ligand information
>7rrg Chain C (length=9) Species:
9606
(Homo sapiens) [
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ALHGGWTTK
Receptor-Ligand Complex Structure
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PDB
7rrg
Immunogenicity and therapeutic targeting of a public neoantigen derived from mutated PIK3CA.
Resolution
2.12 Å
Binding residue
(original residue number in PDB)
Y7 F9 E63 V67 D77 Y84 Y99 R114 D116 T143 K146 W147 E152 Q155 L156 Y159 W167 Y171
Binding residue
(residue number reindexed from 1)
Y7 F9 E63 V67 D77 Y84 Y99 R114 D116 T143 K146 W147 E152 Q155 L156 Y159 W167 Y171
Enzymatic activity
Enzyme Commision number
?
External links
PDB
RCSB:7rrg
,
PDBe:7rrg
,
PDBj:7rrg
PDBsum
7rrg
PubMed
35484264
UniProt
P04439
|HLAA_HUMAN HLA class I histocompatibility antigen, A alpha chain (Gene Name=HLA-A)
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