Structure of PDB 7rke Chain A Binding Site BS01
Receptor Information
>7rke Chain A (length=220) Species:
9606
(Homo sapiens) [
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LSLTADQMVSALLDAEPPILYSFSEASMMGLLTNLADRELVHMINWAKRV
PGFVDLTLHDQVHLLECAWLEILMIGLVWRSMEHPGKLLFAPNLLLDRNQ
GMVEIFDMLLATSSRFRMMNLQGEEFVCLKSIILLNSGVYTLEEKDHIHR
VLDKITDTLIHLMAKAGLTLQQQHQRLAQLLLILSHIRHMSNKGMEHLYS
MKCKNVVPLSDLLLEMLDAH
Ligand information
>7rke Chain C (length=7) Species:
9606
(Homo sapiens) [
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KILHRLL
Receptor-Ligand Complex Structure
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PDB
7rke
A New Chemotype of Chemically Tractable Nonsteroidal Estrogens Based on a Thieno[2,3- d ]pyrimidine Core.
Resolution
1.55 Å
Binding residue
(original residue number in PDB)
I358 K362 L372 V376 L539 E542
Binding residue
(residue number reindexed from 1)
I44 K48 L58 V62 L212 E215
Enzymatic activity
Enzyme Commision number
?
External links
PDB
RCSB:7rke
,
PDBe:7rke
,
PDBj:7rke
PDBsum
7rke
PubMed
35859859
UniProt
P03372
|ESR1_HUMAN Estrogen receptor (Gene Name=ESR1)
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