Structure of PDB 7rk7 Chain A Binding Site BS01
Receptor Information
>7rk7 Chain A (length=238) Species:
9606
(Homo sapiens) [
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GSHSMRYFFTSVSRPGRGEPRFIAVGYVDDTQFVRFDSDAASQRMEPRAP
WIEQEGPEYWDGETRKVKAHSQTHRVDLGTLRGYYNQSEAGSHTVQRMYG
CDVGSDWRFLRGYHQYAYDGKDYIALKEDLRSWTAADMAAQTTKHKWEAA
HVAEQLRAYLEGTCVEWLRRYLENGKETLQRTDPTHTLRCWLSFYPAEIL
TDQTQLVETRPAGDGTFQKWVPSGEQTCHQHEGPKLTL
Ligand information
>7rk7 Chain C (length=9) Species:
9606
(Homo sapiens) [
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YMDGTMSQV
Receptor-Ligand Complex Structure
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PDB
7rk7
The complex between TIL 1383i TCR and human Class I MHC HLA-A2 with the bound Tyrosinase(369-377)(N371D) nonameric peptide
Resolution
2.54 Å
Binding residue
(original residue number in PDB)
Y7 M45 E63 K66 V67 H70 T73 D77 Y84 R97 Y99 T143 W147 L156 Y159 T163 W167 Y171
Binding residue
(residue number reindexed from 1)
Y7 M45 E63 K66 V67 H70 T73 D77 Y84 R97 Y99 T143 W147 L156 Y159 T163 W167 Y171
Enzymatic activity
Enzyme Commision number
?
External links
PDB
RCSB:7rk7
,
PDBe:7rk7
,
PDBj:7rk7
PDBsum
7rk7
PubMed
UniProt
P04439
|HLAA_HUMAN HLA class I histocompatibility antigen, A alpha chain (Gene Name=HLA-A)
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