Structure of PDB 7r8h Chain A Binding Site BS01

Receptor Information
>7r8h Chain A (length=769) Species: 2029104 (Pseudooceanicola lipolyticus) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
MTLETTLFPLEGTGACGASYQLYAVKGLSGLDETEYHKNVNLLVRRLSFS
MKAPFVALSRDGEQFIAVPNYVTEFPVDHRVVRAMVKLVPTGEPLNLRFD
AADDEYDGLRLRYLDFVLQQPLFANHHLWQPGSGQPFFHKKPLKRLDDVD
LYDGVSVRAAKHPEGGFGIVCDARSKFITHTPIGARADRKRLGKLINRSC
LYKMGDHWYQFRIDAVSDWKVGEPSLFEGNVPISLAQQLVRTAGNAAPKS
IIDLDPEGGALEYFTSTNERRMAPAELCFLIEDTHGRRAAKLQRQTILSP
SERRARVNGFIRRYLSELNIGGAKLSAGARAHAFFTETHMPPALSFGNGT
VLAPDTSKDRFQAMQEYSSMRRTMMLDKKVGFFHQDVFPPQTLLLPESVK
KSWGPAFASDFVGTVQELYPAGGYRPEIIEYRDKAYGGGVPGQMKALLEV
AERGEIKSGDVLVMLHRINGAPRAQDKLAAMVCNEFEKRFGKRVQVIHSD
SPGRGYKRIFKNDKPTYVQQRGRGVNIKGYLKGAALNKVCLGNSRWPFVL
RDPLNADVTIGIDVKNNMAVFTMVAEGGRIVRVQRSRSRQREQLLESQVT
QVITEMLSKELPEIKKQVQRVVIHRDGRAWPAEIAGARKTFADMAESGLI
AVDADVSVFEVLKSSPAPLRLFSFEEPTQENPKGVINPVLGSWLKLSEND
GYICTTGAPLLLQGTADPLHVRKAFGPMAIEDALKDVFDLSCLTWPKPDS
CMRLPLTIKLCDIALFDDA
Ligand information
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB7r8h Programmable RNA targeting by bacterial Argonaute nucleases with unconventional guide binding and cleavage specificity.
Resolution2.54 Å
Binding residue
(original residue number in PDB)
R45 F49 K52 R112 F116 Q120 F123 S133 R174 S175 K176 Y202 Y209 R212 L226 L239 S266 R271 M272 D283 H285 T296 L298 R303 R473 I497 H498 S501 Y530 N537 K538 R591 R628 R670 T706 Q713 T715 D717 K747 S750 C751 R753 K759
Binding residue
(residue number reindexed from 1)
R45 F49 K52 R112 F116 Q120 F123 S133 R174 S175 K176 Y202 Y209 R212 L226 L239 S266 R271 M272 D283 H285 T296 L298 R303 R473 I497 H498 S501 Y530 N537 K538 R591 R628 R670 T706 Q713 T715 D717 K747 S750 C751 R753 K759
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0003676 nucleic acid binding

View graph for
Molecular Function
External links
PDB RCSB:7r8h, PDBe:7r8h, PDBj:7r8h
PDBsum7r8h
PubMed35941106
UniProtA0A2M8J4C7

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