Structure of PDB 7qzj Chain A Binding Site BS01

Receptor Information
>7qzj Chain A (length=422) Species: 1203592 (Streptomyces sp. HPH0547) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
DTDRARERDRRHLWHPWSSVRDDRPILVAGEGCRVRDVTGAGYLDAMASA
MNSSCGYAHPALLEAARRQLELLPHFDLSAASHLPAGLAAERIAGLLPAG
LERTFFVNSGSEATEAAVRIAHDHWTNRGEPRDRLVTFAAGYHGTTLVAQ
HLSGLPTNAIHGTAPFPVTRVELPLEPAALRTPEALTLLADAFERAVLDG
PPPAAVMVEPLLNVGGGVVLPDGFLRALRALCDRTGALLIVDEVFCGFGR
TGRMFGFQHDGVTPDLVTMSKGISGGYVPFAALTTTDEVYRSFAADPLLG
GLRYGHTTGGHAVACAVALAVLDVIEERGLVGSAARLGAELLAGLAPLAE
HPEVTDVRGLGLVATVECRQPESAAALVAEAKRQGVLLRQQGRAVMAIPP
LVIDAAEVAELVRAVEQAVARL
Ligand information
Ligand IDPMP
InChIInChI=1S/C8H13N2O5P/c1-5-8(11)7(2-9)6(3-10-5)4-15-16(12,13)14/h3,11H,2,4,9H2,1H3,(H2,12,13,14)
InChIKeyZMJGSOSNSPKHNH-UHFFFAOYSA-N
SMILES
SoftwareSMILES
ACDLabs 10.04O=P(O)(O)OCc1cnc(c(O)c1CN)C
OpenEye OEToolkits 1.5.0Cc1c(c(c(cn1)COP(=O)(O)O)CN)O
CACTVS 3.341Cc1ncc(CO[P](O)(O)=O)c(CN)c1O
FormulaC8 H13 N2 O5 P
Name4'-DEOXY-4'-AMINOPYRIDOXAL-5'-PHOSPHATE;
PYRIDOXAMINE-5'-PHOSPHATE
ChEMBLCHEMBL1235353
DrugBankDB02142
ZINCZINC000001532708
PDB chain7qzj Chain A Residue 501 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
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PDB7qzj Pseudouridine-Modifying Enzymes SapB and SapH Control Entry into the Pseudouridimycin Biosynthetic Pathway.
Resolution1.55 Å
Binding residue
(original residue number in PDB)		S127 G128 S129 Y160 H161 G162 E227 D260 V262 K289
Binding residue
(residue number reindexed from 1)		S109 G110 S111 Y142 H143 G144 E209 D242 V244 K271
Annotation score1
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0004015 adenosylmethionine-8-amino-7-oxononanoate transaminase activity
GO:0008483 transaminase activity
GO:0030170 pyridoxal phosphate binding
Biological Process
GO:0009058 biosynthetic process
GO:0009102 biotin biosynthetic process

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Molecular Function
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Biological Process
External links
PDB RCSB:7qzj, PDBe:7qzj, PDBj:7qzj
PDBsum7qzj
PubMed37005433
UniProtS3AT34

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