Structure of PDB 7qw7 Chain A Binding Site BS01

Receptor Information
>7qw7 Chain A (length=553) Species: 1422 (Geobacillus stearothermophilus) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
TVSRQKATGAHFTPDKLAEVIAKRILDYFKGEKNRVIRVLDPACGDGELL
LAINKVAQSMNIQLELIGVDFDIDAINIANERLSRSGHKNFRLINKDFLE
MEELEPVDIIIANPPYVRTQILGAEKAQKLREKFNLKGRVDLYQAFLVAM
TQQLKSNGIIGVITSNRYLTTKGGESTRKFLVSNFNILEIMDLGDSKFFE
AAVLPAIFFGEKKNKEYQSNVPKFFKIYEQSDIEASSSVNSEFNSLIELL
EVNKSGLYSVEDKTYSISLGKIISPENYKEPWILATEDEYEWFMKVNQNA
YGFIEDFAHVKVGIKTTADSVFIRSDWGELPEEQIPEDKLLRPIISADQA
NKWSVSLVGNNKKVLYTHEIRDGQIKAINLEEFPRAKNYLESHKERLASR
KYVLKANRNWYEIWVPHDPSLWDKPKIIFPDTSPEPKFFYEDKGSVVDGN
CYWIIPKKENSNDILFLIMGICNSKFMSKYHDIAFQNKLYAGRRRYLTQY
VNKYPIPDPESIYSKEIISLVRELVNNKKETQDINEIENRIEKLILRAFD
IES
Ligand information
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB7qw7 Structure of M.BseCI DNA methyltransferase from Geobacillus stearothermophilus.
Resolution2.6 Å
Binding residue
(original residue number in PDB)		K14 G17 H19 N133 P134 Y136 R138 R159 R187 T191 K192 G193 A221 A222 K334 V335 Y475 Y513 R518 T521 Q522
Binding residue
(residue number reindexed from 1)		K6 G9 H11 N113 P114 Y116 R118 R139 R167 T171 K172 G173 A201 A202 K311 V312 Y452 Y490 R495 T498 Q499
Enzymatic activity
Enzyme Commision number 2.1.1.72: site-specific DNA-methyltransferase (adenine-specific).
Gene Ontology
Molecular Function
GO:0003676 nucleic acid binding
GO:0003677 DNA binding
GO:0008168 methyltransferase activity
GO:0009007 site-specific DNA-methyltransferase (adenine-specific) activity
Biological Process
GO:0006304 DNA modification
GO:0009307 DNA restriction-modification system
GO:0032259 methylation

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Molecular Function
View graph for
Biological Process
External links
PDB RCSB:7qw7, PDBe:7qw7, PDBj:7qw7
PDBsum7qw7
PubMed
UniProtP43423|MTC1_GEOSE Type II methyltransferase M.BseCI (Gene Name=bseCIM)

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