Structure of PDB 7qw6 Chain A Binding Site BS01

Receptor Information
>7qw6 Chain A (length=556) Species: 1422 (Geobacillus stearothermophilus) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
TVSRQKATGAHFTPDKLAEVIAKRILDYFKGEKNRVIRVLDPACGDGELL
LAINKVAQSMNIQLELIGVDFDIDAINIANERLSRSGHKNFRLINKDFLE
MEELEPVDIIIANPPYVRTQILGAEKAQKLREKFNLKGRVDLYQAFLVAM
TQQLKSNGIIGVITSNRYLTTKGGESTRKFLVSNFNILEIMDLGDSKFFE
AAVLPAIFFGEKKNKEYQKENSNVPKFFKIYEQSDIEASSSVNSEFNSLI
ELLEVNKSGLYSVEDKTYSISLGKIISPENYKEPWILATEDEYEWFMKVN
QNAYGFIEDFAHVKVGIKTTADSVFIRSDWGELPEEQIPEDKLLRPIISA
DQANKWSVSLVGNNKKVLYTHEIRDGQIKAINLEEFPRAKNYLESHKERL
ASRKYVLKANRNWYEIWVPHDPSLWDKPKIIFPDTSPEPKFFYEDKGSVV
DGNCYWIIPKKENSNDILFLIMGICNSKFMSKYHDIAFQNKLYAGRRRYL
TQYVNKYPIPDPESIYSKEIISLVRELVNNKKETQDINEIENRIEKLILR
AFDIES
Ligand information
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

[Spin on] [Spin off] [Reset]
[High quality] [Low quality]
[White background] [Black background]
[Spin on] [Spin off] [Reset]
[High quality] [Low quality]
[White background] [Black background]
PDB7qw6 Structure of M.BseCI DNA methyltransferase from Geobacillus stearothermophilus.
Resolution2.4 Å
Binding residue
(original residue number in PDB)		K14 G17 H19 N133 P134 Y136 R138 R159 R187 T191 K192 G193 F219 A221 A222 K334 V335 Y475 Y513 R518 T521 Q522
Binding residue
(residue number reindexed from 1)		K6 G9 H11 N113 P114 Y116 R118 R139 R167 T171 K172 G173 F199 A201 A202 K314 V315 Y455 Y493 R498 T501 Q502
Enzymatic activity
Enzyme Commision number 2.1.1.72: site-specific DNA-methyltransferase (adenine-specific).
Gene Ontology
Molecular Function
GO:0003676 nucleic acid binding
GO:0003677 DNA binding
GO:0008168 methyltransferase activity
GO:0009007 site-specific DNA-methyltransferase (adenine-specific) activity
Biological Process
GO:0006304 DNA modification
GO:0009307 DNA restriction-modification system
GO:0032259 methylation

View graph for
Molecular Function
View graph for
Biological Process
External links
PDB RCSB:7qw6, PDBe:7qw6, PDBj:7qw6
PDBsum7qw6
PubMed
UniProtP43423|MTC1_GEOSE Type II methyltransferase M.BseCI (Gene Name=bseCIM)

[Back to BioLiP]