Structure of PDB 7qw5 Chain A Binding Site BS01

Receptor Information
>7qw5 Chain A (length=544) Species: 1422 (Geobacillus stearothermophilus) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
VSRQKATGAHFTPDKLAEVIAKRILDYFKGEKNRVIRVLDPACGDGELLL
AINKVAQSMNIQLELIGVDFDIDAINIANERLSRSGHKNFRLINKDFLEM
LEPVDIIIANPPYVRTQILGAEKAQKLREKFNLKGRVDLYQAFLVAMTQQ
LKSNGIIGVITSNRYLTTKGGESTRKFLVSNFNILEIMDLGDSKFFEAAV
LPAIFFGEKKNKESNVPKFFKIYEQSDIEASSSVNSEFNSLIELLEVNKS
GLYSVEDKTYSISLGKIISPENYKEPWILATEDEYEWFMKVNQNAYGFIE
DFAHVKVGIKTTADSVFIRSDWGELPEEQIPEDKLLRPIISADQANKWSV
SGNNKKVLYTHEIRDGQIKAINLEEFPRAKNYLESHKERLASRKYVLKAN
RNWYEIWVPHDPSLWDKPKIIFPDTSPEPKFFYEDKGSVVDGNCYWIIPK
KENSNDILFLIMGICNSKFMSKYHDIAFQNKLYAGRRRYLTQYVNKYPIP
DPESIYSKEIISLVRELVNNETQDINEIENRIEKLILRAFDIES
Ligand information
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB7qw5 Structure of M.BseCI DNA methyltransferase from Geobacillus stearothermophilus.
Resolution2.3 Å
Binding residue
(original residue number in PDB)		K14 G17 H19 N133 P134 Y136 R138 R159 R187 K192 G193 F219 A221 A222 K334 V335 H440 Y475 L512 Y513 R518 T521 Q522
Binding residue
(residue number reindexed from 1)		K5 G8 H10 N110 P111 Y113 R115 R136 R164 K169 G170 F196 A198 A199 K306 V307 H410 Y445 L482 Y483 R488 T491 Q492
Enzymatic activity
Enzyme Commision number 2.1.1.72: site-specific DNA-methyltransferase (adenine-specific).
Gene Ontology
Molecular Function
GO:0003676 nucleic acid binding
GO:0003677 DNA binding
GO:0008168 methyltransferase activity
GO:0009007 site-specific DNA-methyltransferase (adenine-specific) activity
Biological Process
GO:0006304 DNA modification
GO:0009307 DNA restriction-modification system
GO:0032259 methylation

View graph for
Molecular Function
View graph for
Biological Process
External links
PDB RCSB:7qw5, PDBe:7qw5, PDBj:7qw5
PDBsum7qw5
PubMed
UniProtP43423|MTC1_GEOSE Type II methyltransferase M.BseCI (Gene Name=bseCIM)

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