Structure of PDB 7qux Chain A Binding Site BS01

Receptor Information
>7qux Chain A (length=330) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
GSSGPVPSRARVYTDVNTHRPREYWDYESHVVEWGNQDDYQLVRKLGRGK
YSEVFEAINITNNEKVVVKILKPVKKKKIKREIKILENLRGGPNIITLAD
IVKDPVSRTPALVFEHVNNTDFKQLYQTLTDYDIRFYMYEILKALDYCHS
MGIMHRDVKPHNVMIDHEHRKLRLIDWGLAEFYHPGQEYNVRVASRYFKG
PELLVDYQMYDYSLDMWSLGCMLASMIFRKEPFFHGHDNYDQLVRIAKVL
GTEDLYDYIDKYNIELDPRFNDILGRHSRKRWERFVHSENQHLVSPEALD
FLDKLLRYDHQSRLTAREAMEHPYFYTVVK
Ligand information
Receptor-Ligand Complex Structure
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PDB7qux Development of small cyclic peptides targeting the CK2 alpha / beta interface.
Resolution1.48 Å
Binding residue
(original residue number in PDB)		Q36 Y39 Q40 L41 F54 V67 I69 D103 T108
Binding residue
(residue number reindexed from 1)		Q37 Y40 Q41 L42 F55 V68 I70 D104 T109
Enzymatic activity
Enzyme Commision number 2.7.11.1: non-specific serine/threonine protein kinase.
Gene Ontology
Molecular Function
GO:0004672 protein kinase activity
GO:0004674 protein serine/threonine kinase activity
GO:0005524 ATP binding
Biological Process
GO:0006468 protein phosphorylation

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Molecular Function
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Biological Process
External links
PDB RCSB:7qux, PDBe:7qux, PDBj:7qux
PDBsum7qux
PubMed35343996
UniProtP68400|CSK21_HUMAN Casein kinase II subunit alpha (Gene Name=CSNK2A1)

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