Structure of PDB 7qrd Chain A Binding Site BS01

Receptor Information
>7qrd Chain A (length=364) Species: 10090 (Mus musculus) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
SVFSERTEESSAVQYFQFYGYLSQQQNMMQDYVRTGTYQRAILQNHTDFK
DKIVLDVGCGSGILSFFAAQAGARKIYAVEASTMAQHAEVLVKSNNLTDR
IVVIPGKVEEVSLPEQVDIIISEPMGYMLFNERMLESYLHAKKYLKPSGN
MFPTIGDVHLAPFTDEQLYMEQFTKANFWYQPSFHGVDLSALRGAAVDEY
FRQPVVDTFDIRILMAKSVKYTVNFLEAKEGDLHRIEIPFKFHMLHSGLV
HGLAFWFDVAFIGSIMTVWLSTAPTEPLTHWYQVRCLFQSPLFAKAGDTL
SGTCLLIANKRQSYDISIVAQVDQTGSKSSNLLDLKNPFFRYTGTTPSPP
PGSHYTSPSENMWN
Ligand information
Receptor-Ligand Complex Structure
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PDB7qrd CARM1 Transition State Mimics
Resolution2.0 Å
Binding residue
(original residue number in PDB)
F153 Y154 N162 M163 E258 M260 Y262 E267 T414 H415 Y417 K471 N472 P473 F475
Binding residue
(residue number reindexed from 1)
F18 Y19 N27 M28 E123 M125 Y127 E132 T279 H280 Y282 K336 N337 P338 F340
Enzymatic activity
Enzyme Commision number 2.1.1.319: type I protein arginine methyltransferase.
Gene Ontology
Molecular Function
GO:0016274 protein-arginine N-methyltransferase activity
Biological Process
GO:0018216 peptidyl-arginine methylation

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Molecular Function

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Biological Process
External links
PDB RCSB:7qrd, PDBe:7qrd, PDBj:7qrd
PDBsum7qrd
PubMed
UniProtQ9WVG6|CARM1_MOUSE Histone-arginine methyltransferase CARM1 (Gene Name=Carm1)

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