Structure of PDB 7qpb Chain A Binding Site BS01

Receptor Information
>7qpb Chain A (length=106) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
NLDFQALEETTEYDGGYTRDSVLIREFWEIVHSFTDEQKRLFLQFTTGTD
RAPVGGLGKLKMIIAKNGPDTERLPTSHTCFNVLLLPEYSSKEKLKERLL
KAITYA
Ligand information
Receptor-Ligand Complex Structure
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PDB7qpb Display Selection of a Hybrid Foldamer-Peptide Macrocycle.
Resolution2.342 Å
Binding residue
(original residue number in PDB)
D754 G755 A805 V823
Binding residue
(residue number reindexed from 1)
D14 G15 A65 V83
Enzymatic activity
Enzyme Commision number 2.3.2.26: HECT-type E3 ubiquitin transferase.
Gene Ontology
Molecular Function
GO:0004842 ubiquitin-protein transferase activity
GO:0061630 ubiquitin protein ligase activity
Biological Process
GO:0000209 protein polyubiquitination

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Molecular Function

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Biological Process
External links
PDB RCSB:7qpb, PDBe:7qpb, PDBj:7qpb
PDBsum7qpb
PubMed37707879
UniProtQ05086|UBE3A_HUMAN Ubiquitin-protein ligase E3A (Gene Name=UBE3A)

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