Structure of PDB 7qfw Chain A Binding Site BS01

Receptor Information
>7qfw Chain A (length=823) Species: 559292 (Saccharomyces cerevisiae S288C) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
IDINTKIFNSVAEVFQKAQGSYAGHRKHIAVLKKIQSKAVEQGYEDAFNF
WFDKLVTKILPLKKNEIIGDRIVKLVAAFIASLERELILAKKQNYKLTND
EEGIFSRFVDQFIRHVLRGVESPDKNVRFRVLQLLAVIMDNIGEIDESLF
NLLILSLNKRIYDREPTVRIQAVFCLTKFQDEEQTEHNFEATRTLVASIQ
NDPSAEVRRAAMLNLINDNNTRPYILERARDVNIVNRRLVYSRILKSMGR
KCFDDIEPHIFDQLIEWGLEDRELSVRNACKRLIAHDWLNALDGDLIELL
EKLDVSRSSVCVKAIEALFQSRPDILSKIKFPESIWKDFTVEIAFLFRAI
YLYCLDNNITEMLEENFPEASKLSEHLNHYILLRYHHNHFDYNTLEFIIE
QLSIAAERYDYSDEVGRRSMLTVVRNMLALTTLSEPLIKIGIRVMKSLSI
NEKDFVTMAIEIINDIRDDDIEKQEQEEKEKEASSATIVLCLTRSSYMLE
LVNTPLTENILIASLMDTLITPAVRNTAPNIRELGVKNLGLCCLLDVKLA
IDNMYILGMCVSKGNASLKYIALQVIVDIFSVHGNTVVDGEGKVDSISLH
KIFYKVLKNNGLPECQVIAAEGLCKLFLADVFTDDDLFETLVLSYFSPIN
SSNEALVQAFAFCIPVYCFSHPAHQQRMSRTAADILLRLCVLWDDLQSSV
IPEVDREAMLKPNIIFQQLLFWTDPRNLVNQTGSTKKDTVQLTFLIDVLK
IYAQIEKKEIKKMIITNINAIFLSSEQDYSTLKELLEYSDDIAENDNLDN
VSKNALDKLRNNLNSLIEEINER
Ligand information
Receptor-Ligand Complex Structure
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PDB7qfw A hold-and-feed mechanism drives directional DNA loop extrusion by condensin.
Resolution3.86 Å
Binding residue
(original residue number in PDB)		K70 N71 R170 R224 N800 Q804 T853 N854 N856 A857
Binding residue
(residue number reindexed from 1)		K64 N65 R164 R209 N713 Q717 T766 N767 N769 A770
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0003682 chromatin binding
GO:0005515 protein binding
Biological Process
GO:0000070 mitotic sister chromatid segregation
GO:0007076 mitotic chromosome condensation
GO:0007130 synaptonemal complex assembly
GO:0010032 meiotic chromosome condensation
GO:0030261 chromosome condensation
GO:0051301 cell division
GO:0051307 meiotic chromosome separation
GO:0070058 tRNA gene clustering
GO:0070550 rDNA chromatin condensation
GO:1903342 negative regulation of meiotic DNA double-strand break formation
Cellular Component
GO:0000793 condensed chromosome
GO:0000796 condensin complex
GO:0005634 nucleus
GO:0005694 chromosome
GO:0005737 cytoplasm

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:7qfw, PDBe:7qfw, PDBj:7qfw
PDBsum7qfw
PubMed35653469
UniProtQ06680|CND3_YEAST Condensin complex subunit 3 (Gene Name=YCG1)

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