Structure of PDB 7q45 Chain A Binding Site BS01
Receptor Information
>7q45 Chain A (length=369) Species:
9606
(Homo sapiens) [
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RTKVFVWGLNDKDQLGGLKGSKIKVPSFSETLSALNVVQVAGGSKSLFAV
TVEGKVYACGEATNGRLGLGISSGTVPIPRQITALSSYVVKKVAVHSGGR
HATALTVDGKVFSWGEGDDGKLGHFSRMNCDKPRLIEALKTKRIRDIACG
SSHSAALTSSGELYTWGLGEYGRLGHGDNTTQLKPKMVKVLLGHRVIQVA
CGSRDAQTLALTDEGLVFSWGDGDFGKLGRGGSEGCNIPQNIERLNGQGV
CQIECGAQFSLALTKSGVVWTWGKGDYFRLGHGSDVHVRKPQVVEGLRGK
KIVHVAVGALHCLAVTDSGQVYAWGDNDHGQQGNGTTTVNRKPTLVQGLE
GQKITRVACGSSHSVAWTT
Ligand information
>7q45 Chain B (length=9) Species:
9606
(Homo sapiens) [
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DDDKDEDTH
Receptor-Ligand Complex Structure
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PDB
7q45
Crystal structure of RCC1-Like domain 2 of ubiquitin ligase HERC2 in complex with DXDKDED motif of Myelin transcription factor 1
Resolution
2.1 Å
Binding residue
(original residue number in PDB)
D2968 S2978 K2979 K3002 R3161 A3214 Y3234 L3267 D3283 D3285 H3286 S3318 S3319
Binding residue
(residue number reindexed from 1)
D11 S21 K22 K45 R204 A257 Y277 L310 D326 D328 H329 S361 S362
Enzymatic activity
Enzyme Commision number
2.3.2.26
: HECT-type E3 ubiquitin transferase.
External links
PDB
RCSB:7q45
,
PDBe:7q45
,
PDBj:7q45
PDBsum
7q45
PubMed
UniProt
O95714
|HERC2_HUMAN E3 ubiquitin-protein ligase HERC2 (Gene Name=HERC2)
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