Structure of PDB 7q41 Chain A Binding Site BS01
Receptor Information
>7q41 Chain A (length=369) Species:
9606
(Homo sapiens) [
Search protein sequence
] [
Download receptor structure
] [
Download structure with residue number starting from 1
] [
View receptor structure
]
RTKVFVWGLNDKDQLGGLKGSKIKVPSFSETLSALNVVQVAGGSKSLFAV
TVEGKVYACGEATNGRLGLGISSGTVPIPRQITALSSYVVKKVAVHSGGR
HATALTVDGKVFSWGEGDDGKLGHFSRMNCDKPRLIEALKTKRIRDIACG
SSHSAALTSSGELYTWGLGEYGRLGHGDNTTQLKPKMVKVLLGHRVIQVA
CGSRDAQTLALTDEGLVFSWGDGDFGKLGRGGSEGCNIPQNIERLNGQGV
CQIECGAQFSLALTKSGVVWTWGKGDYFRLGHGSDVHVRKPQVVEGLRGK
KIVHVAVGALHCLAVTDSGQVYAWGDNDHGQQGNGTTTVNRKPTLVQGLE
GQKITRVACGSSHSVAWTT
Ligand information
>7q41 Chain B (length=9) Species:
9606
(Homo sapiens) [
Search peptide sequence
] [
Download ligand structure
] [
Download structure with residue number starting from 1
] [
View ligand structure
]
KDEDKDEDE
Receptor-Ligand Complex Structure
Global view
Local view
Structure summary
[
Spin on
] [
Spin off
] [
Reset
]
[
High quality
] [
Low quality
]
[
White background
] [
Black background
]
[
Spin on
] [
Spin off
] [
Reset
]
[
High quality
] [
Low quality
]
[
White background
] [
Black background
]
PDB
7q41
Crystal structure of RCC1-Like domain 2 of ubiquitin ligase HERC2 in complex with DXDKDED motif of ubiquitin-protein ligase E3A (E6AP)
Resolution
3.01478 Å
Binding residue
(original residue number in PDB)
L2966 D2968 K2979 K3002 R3161 A3214 Y3234 L3267 D3285 H3286 S3318
Binding residue
(residue number reindexed from 1)
L9 D11 K22 K45 R204 A257 Y277 L310 D328 H329 S361
Enzymatic activity
Enzyme Commision number
2.3.2.26
: HECT-type E3 ubiquitin transferase.
External links
PDB
RCSB:7q41
,
PDBe:7q41
,
PDBj:7q41
PDBsum
7q41
PubMed
UniProt
O95714
|HERC2_HUMAN E3 ubiquitin-protein ligase HERC2 (Gene Name=HERC2)
[
Back to BioLiP
]
