Structure of PDB 7prx Chain A Binding Site BS01
Receptor Information
>7prx Chain A (length=248) Species:
9606
(Homo sapiens) [
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TPTLVSLLEVIEPEVLYAGYDSSVPDSTWRIMTTLNMLGGRQVIAAVKWA
KAIPGFRNLHLDDQMTLLQYSWMFLMAFALGWRSYRQSSANLLCFAPDLI
INEQRMTLPCMYDQCKHMLYVSSELHRLQVSYEEYLCMKTLLLLSSVPKD
GLKSQELFDEIRMTYIKELGKAIVKREGNSSQNWQRFYQLTKLLDSMHEV
VENLLNYCFQTFLDKTMSIEFPEMLAEIITNQIPKYSNGNIKKLLFHQ
Ligand information
>7prx Chain B (length=19) Species:
9606
(Homo sapiens) [
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PPQEAEEPSLLKKLLLAPA
Receptor-Ligand Complex Structure
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PDB
7prx
Quaternary glucocorticoid receptor structure highlights allosteric interdomain communication.
Resolution
2.2 Å
Binding residue
(original residue number in PDB)
I572 V575 K579 R585 L589 M593 E751 M752 E755
Binding residue
(residue number reindexed from 1)
I44 V47 K51 R57 L61 M65 E223 M224 E227
Enzymatic activity
Enzyme Commision number
?
External links
PDB
RCSB:7prx
,
PDBe:7prx
,
PDBj:7prx
PDBsum
7prx
PubMed
36747092
UniProt
P04150
|GCR_HUMAN Glucocorticoid receptor (Gene Name=NR3C1)
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