Structure of PDB 7pli Chain A Binding Site BS01

Receptor Information
>7pli Chain A (length=457) Species: 83333 (Escherichia coli K-12) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
MTAFSTLNVLPPAQLTNLNELGYLTMTPVQAAALPAILAGKDVRVQAKTG
SGKTAAFGLGLLQQIDASLFQTQALVLCPTRELADQVAGELRRLARFLPN
TKILTLCGGQPFGMQRDSLQHAPHIIVATPGRLLDHLQKGTVSLDALNTL
VMDEADRMLDMGFSDAIDDVIRFAPASRQTLLFSATWPEAIAAISGRVQR
DPLAIEIDSTDALPPIEQQFYETSSKGKIPLLQRLLSLHQPSSCVVFCNT
KKDCQAVCDALNEVGQSALSLHGDLEQRDRDQTLVRFANGSARVLVATDV
AARGLDIKSLELVVNFELAWDPEVHVHRIGRTARAGNSGLAISFCAPEEA
QRANIISDMLQIKLNWQTPPANSSIATLEAEMATLCIDGGKKAKMRPGDV
LGALTGDIGLDGADIGKIAVHPAHVYVAVRQAVAHKAWKQLQGGKIKGKT
CRVRLLK
Ligand information
>7pli Chain D (length=22) [Search RNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
ggacauauggcuguucgccauu
......<<<<<.....>>>>>.
Receptor-Ligand Complex Structure
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PDB7pli Structural basis for RNA-duplex unwinding by the DEAD-box helicase DbpA.
Resolution2.5 Å
Binding residue
(original residue number in PDB)		F70 R96 N100 K102 S118 H121 K391 K392 K394 R396 G398 D399 L401 G402 A403 T405 I415 G416 I418 K447 G448
Binding residue
(residue number reindexed from 1)		F70 R96 N100 K102 S118 H121 K391 K392 K394 R396 G398 D399 L401 G402 A403 T405 I415 G416 I418 K447 G448
Enzymatic activity
Enzyme Commision number 3.6.4.13: RNA helicase.
Gene Ontology
Molecular Function
GO:0003676 nucleic acid binding
GO:0003723 RNA binding
GO:0003724 RNA helicase activity
GO:0004386 helicase activity
GO:0005524 ATP binding
GO:0016787 hydrolase activity
GO:0016887 ATP hydrolysis activity
GO:0019843 rRNA binding
GO:0033677 DNA/RNA helicase activity
GO:0034458 3'-5' RNA helicase activity
GO:0043531 ADP binding
Biological Process
GO:0000027 ribosomal large subunit assembly
GO:0042254 ribosome biogenesis
Cellular Component
GO:0005737 cytoplasm
GO:0005829 cytosol

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:7pli, PDBe:7pli, PDBj:7pli
PDBsum7pli
PubMed37221012
UniProtP21693|DBPA_ECOLI ATP-dependent RNA helicase DbpA (Gene Name=dbpA)

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