Structure of PDB 7pdv Chain A Binding Site BS01

Receptor Information
>7pdv Chain A (length=107) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
TIMLRGLPTTITESDIREMMESFEGPQPADVRLMKRKTGVSRGFAFVEFY
HLQDATSWMEANQKKLVIQGKHIAMHYSNPRPKFEDWLCNKCGLNNFRKR
LKCFRCG
Ligand information
Ligand IDZN
InChIInChI=1S/Zn/q+2
InChIKeyPTFCDOFLOPIGGS-UHFFFAOYSA-N
SMILES
SoftwareSMILES
CACTVS 3.341[Zn++]
ACDLabs 10.04
OpenEye OEToolkits 1.5.0
[Zn+2]
FormulaZn
NameZINC ION
ChEMBLCHEMBL1236970
DrugBankDB14532
ZINC
PDB chain7pdv Chain A Residue 201 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

[Spin on] [Spin off] [Reset]
[High quality] [Low quality]
[White background] [Black background]

[Spin on] [Spin off] [Reset]
[High quality] [Low quality]
[White background] [Black background]
PDB7pdv Structural basis for specific RNA recognition by the alternative splicing factor RBM5.
Resolution3.49 Å
Binding residue
(original residue number in PDB)
C96 C99 C110
Binding residue
(residue number reindexed from 1)
C89 C92 C103
Annotation score4
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0003676 nucleic acid binding
GO:0003723 RNA binding

View graph for
Molecular Function
External links
PDB RCSB:7pdv, PDBe:7pdv, PDBj:7pdv
PDBsum7pdv
PubMed37454201
UniProtP52756|RBM5_HUMAN RNA-binding protein 5 (Gene Name=RBM5)

[Back to BioLiP]