Structure of PDB 7pdc Chain A Binding Site BS01

Receptor Information
>7pdc Chain A (length=30) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
LGDFFRKSKEKIGKEFKRIVQRIKDFLRNL
Ligand information
>7pdc Chain B (length=27) Species: 9606 (Homo sapiens) [Search peptide sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
FFRKSKEKIGKEFKRIVQRIKDFLRNL
Receptor-Ligand Complex Structure
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PDB7pdc The structure of the antimicrobial human cathelicidin LL-37 shows oligomerization and channel formation in the presence of membrane mimics.
Resolution1.83 Å
Binding residue
(original residue number in PDB)
E16 I20 R23 F27
Binding residue
(residue number reindexed from 1)
E15 I19 R22 F26
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Biological Process
GO:0042742 defense response to bacterium

View graph for
Biological Process
External links
PDB RCSB:7pdc, PDBe:7pdc, PDBj:7pdc
PDBsum7pdc
PubMed33060695
UniProtP49913|CAMP_HUMAN Cathelicidin antimicrobial peptide (Gene Name=CAMP)

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