Structure of PDB 7pbs Chain A Binding Site BS01

Receptor Information
>7pbs Chain A (length=312) Species: 1308 (Streptococcus thermophilus) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
TLRPQYFKEYIGQDKVKDQLKIFIEAAKLRDEALDHTLLFGPPGLGKTTM
AFVIANEMGVNLKQTSGPAIEKAGDLVAILNDLEPGDILFIDEIHRMPMA
VEEVLYSAMEDYYIDIMIGAGETSRSVHLDLPPFTLVGATTRAGMLSNPL
RARFGINGHMEYYELPDLTEIVERTSEIFEMTITPEAALELARRSRGTPR
IANRLLKRVRDYAQIMGDGVIDDKIADQALTMLDVDHEGLDYVDQKILRT
MIEMYGGGPVGLGTLSVNIAEERETVEDMYEPYLIQKGFIMRTRTGRVAT
AKAYEHMGYDYT
Ligand information
Receptor-Ligand Complex Structure
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PDB7pbs Mechanism of AAA+ ATPase-mediated RuvAB-Holliday junction branch migration.
Resolution3.3 Å
Binding residue
(original residue number in PDB)
G279 T282 T313
Binding residue
(residue number reindexed from 1)
G261 T264 T295
Enzymatic activity
Enzyme Commision number 3.6.4.12: DNA helicase.
Gene Ontology
Molecular Function
GO:0000400 four-way junction DNA binding
GO:0003677 DNA binding
GO:0005524 ATP binding
GO:0009378 four-way junction helicase activity
GO:0016787 hydrolase activity
GO:0016887 ATP hydrolysis activity
Biological Process
GO:0006281 DNA repair
GO:0006310 DNA recombination
GO:0032508 DNA duplex unwinding
Cellular Component
GO:0005737 cytoplasm
GO:0048476 Holliday junction resolvase complex

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Molecular Function

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Biological Process

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Cellular Component
External links
PDB RCSB:7pbs, PDBe:7pbs, PDBj:7pbs
PDBsum7pbs
PubMed36002576
UniProtQ5M2B1|RUVB_STRT2 Holliday junction branch migration complex subunit RuvB (Gene Name=ruvB)

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