Structure of PDB 7pab Chain A Binding Site BS01

Receptor Information
>7pab Chain A (length=415) Species: 10335 (Human alphaherpesvirus 3) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
GSHMLEMGDNLLQRIRLVVPSALQCCDGDLPIFDPQRPPARCVFQFNGED
NVSEAFPVEYIMRLMANWAQVDCDPYIKIQNTGVSVLFQGFFFRPTNAPV
AEVSIDSNNVILSSTLSTGINLSALESIKRGGGIDRRPLQALMWVNCFVR
MPYVQLSFRFMGPEDPSRTIKLMARATDAYMSVYRHYFNYIARSPPEELA
TVRGLIVPIIKTTPVTLPFNLGQTVADNCLSLSGMGYHLGLGGYCPTCTA
TDRAALILAYVQQLNNIYEYRVFLASILALSDRASAEPLLSSVLAQPELF
FMYHIMREGGMRDIRVLFYRDGDAGGFMMYVIFPGKSVHLHYRLIDHIQA
ACRGYKIVAHVWQTTFLLSVCRNTVVPSIGTSDVYCKMCDLNFDGELLLE
YKRLYALFDDFVPPR
Ligand information
Ligand IDZN
InChIInChI=1S/Zn/q+2
InChIKeyPTFCDOFLOPIGGS-UHFFFAOYSA-N
SMILES
SoftwareSMILES
CACTVS 3.341[Zn++]
ACDLabs 10.04
OpenEye OEToolkits 1.5.0		[Zn+2]
FormulaZn
NameZINC ION
ChEMBLCHEMBL1236970
DrugBankDB14532
ZINC
PDB chain7pab Chain A Residue 502 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB7pab The crystal structure of the varicella-zoster Orf24-Orf27 nuclear egress complex spotlights multiple determinants of herpesvirus subfamily specificity.
Resolution2.1 Å
Binding residue
(original residue number in PDB)		C1128 C1144 C1147 H1251
Binding residue
(residue number reindexed from 1)		C229 C245 C248 H339
Annotation score4
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Biological Process
GO:0046765 viral budding from nuclear membrane
GO:0046802 exit of virus from host cell nucleus by nuclear egress

View graph for
Biological Process
External links
PDB RCSB:7pab, PDBe:7pab, PDBj:7pab
PDBsum7pab
PubMed35074430
UniProtQ6QCM8;
Q6QCN1

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