Structure of PDB 7p99 Chain A Binding Site BS01

Receptor Information
>7p99 Chain A (length=266) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
LCVQWKNAYALCWLDCILSALVHSEELKNTVTGLCSKEESIFWRLLTKYN
QANTLLYTSQLTSEIFAEIETCLNEVRDEIFISLQPQLRCTLGDMESPVF
AFPLLLKLETHIEKLFLYSFSWDFECSQCGHQYQNRHMKSLVTFTNVIPE
WHPLNAAHFGPCNNCNSKSQIRKMVLEKVSPIFMLHFVEGLPQNDLQHYA
FHFEGCLYQITSVIQYRANNHFITWILDADGSWLECDDLKGPCSERHKKF
EVPASEIHIVIWERKI
Ligand information
Ligand IDZN
InChIInChI=1S/Zn/q+2
InChIKeyPTFCDOFLOPIGGS-UHFFFAOYSA-N
SMILES
SoftwareSMILES
CACTVS 3.341[Zn++]
ACDLabs 10.04
OpenEye OEToolkits 1.5.0		[Zn+2]
FormulaZn
NameZINC ION
ChEMBLCHEMBL1236970
DrugBankDB14532
ZINC
PDB chain7p99 Chain A Residue 601 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
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PDB7p99 Structural basis for the SUMO protease activity of the atypical ubiquitin-specific protease USPL1.
Resolution1.8 Å
Binding residue
(original residue number in PDB)		C361 C364 C397 C400
Binding residue
(residue number reindexed from 1)		C126 C129 C162 C165
Annotation score4
Enzymatic activity
Enzyme Commision number 3.4.22.-
Gene Ontology
Biological Process
GO:0030576 Cajal body organization

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Molecular Function
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Biological Process
External links
PDB RCSB:7p99, PDBe:7p99, PDBj:7p99
PDBsum7p99
PubMed35383180
UniProtQ5W0Q7|USPL1_HUMAN SUMO-specific isopeptidase USPL1 (Gene Name=USPL1)

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