Structure of PDB 7p56 Chain A Binding Site BS01

Receptor Information
>7p56 Chain A (length=346) Species: 5702 (Trypanosoma brucei brucei) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
AAEKGFKQAFWQPLCQVSEELDDQPKGALFTLQAAASKIQKMRDAALRAS
IYAEINHGTNRAKAAVIVANHYAMKADSGLEALKQTLSSQEVTATATASY
LKGRIDEYLNLLLQTKESGTSGCMMDTSGTNTVTKAGGTIGGVPCKLQLS
PIQPKRPAATYLGKAGYVGLTRQADAANNFHDNDAECRLASGHNTNGLGK
SGQLSAAVTMAAGYVTVANSQTAVTVQALDALQEASGAAHQPWIDAWKAK
KALTGAETAEFRNETAGIAGKTGVTKLVEEALLQTELKKYFSGHENEQWT
AIEKLISEQPVAQNLVGDQPTKLGELEGNAKLTTILAYYRMETAGK
Ligand information
Ligand IDCA
InChIInChI=1S/Ca/q+2
InChIKeyBHPQYMZQTOCNFJ-UHFFFAOYSA-N
SMILES
SoftwareSMILES
CACTVS 3.341[Ca++]
ACDLabs 10.04
OpenEye OEToolkits 1.5.0		[Ca+2]
FormulaCa
NameCALCIUM ION
ChEMBL
DrugBankDB14577
ZINC
PDB chain7p56 Chain A Residue 501 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB7p56 Immunodominant surface epitopes power immune evasion in the African trypanosome.
Resolution1.735 Å
Binding residue
(original residue number in PDB)		G155 D208 N209 D210
Binding residue
(residue number reindexed from 1)		G129 D182 N183 D184
Annotation score4
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Biological Process
GO:0042783 evasion of host immune response

View graph for
Biological Process
External links
PDB RCSB:7p56, PDBe:7p56, PDBj:7p56
PDBsum7p56
PubMed36943866
UniProtP26332|VSM2_TRYBB Variant surface glycoprotein MITAT 1.2

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