Structure of PDB 7p47 Chain A Binding Site BS01

Receptor Information
>7p47 Chain A (length=187) Species: 4932 (Saccharomyces cerevisiae) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
HMLEARDLSNIYQQCYKQIDETINQLVDSTSPSTIGIEEQVADITSTYKL
LSTYESESNNTDTLKILKVLPYIWNDPTCVIPDLQNPADEDDLQIEGGKI
ELTCPITCKPYEAPLISRKCNHVFDRDGIQNYLQGYTTRDCPQAACSQVV
SMRDFVRDPIMELRCKIAKMKESQEQDKRSSQAIDVL
Ligand information
Ligand IDZN
InChIInChI=1S/Zn/q+2
InChIKeyPTFCDOFLOPIGGS-UHFFFAOYSA-N
SMILES
SoftwareSMILES
CACTVS 3.341[Zn++]
ACDLabs 10.04
OpenEye OEToolkits 1.5.0		[Zn+2]
FormulaZn
NameZINC ION
ChEMBLCHEMBL1236970
DrugBankDB14532
ZINC
PDB chain7p47 Chain A Residue 301 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
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PDB7p47 Structural basis for the E3 ligase activity enhancement of yeast Nse2 by SUMO-interacting motifs.
Resolution3.314 Å
Binding residue
(original residue number in PDB)		C200 H202 C221 C226
Binding residue
(residue number reindexed from 1)		C120 H122 C141 C146
Annotation score4
Enzymatic activity
Enzyme Commision number 2.3.2.-
Gene Ontology
Molecular Function
GO:0008270 zinc ion binding
GO:0019789 SUMO transferase activity
Biological Process
GO:0000724 double-strand break repair via homologous recombination
Cellular Component
GO:0030915 Smc5-Smc6 complex

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:7p47, PDBe:7p47, PDBj:7p47
PDBsum7p47
PubMed34853311
UniProtP38632|NSE2_YEAST E3 SUMO-protein ligase MMS21 (Gene Name=MMS21)

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