Structure of PDB 7p43 Chain A Binding Site BS01

Receptor Information
>7p43 Chain A (length=687) Species: 284593 (Nakaseomyces glabratus CBS 138) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
MSLTKIPENVQGAVSIDPWLEPFADVLSERRYLADKWLYDIKHATPDGSE
QSLVDFARNAYKTYGLHANQQTKEIVYREWAPNAQRAFLVGEFNNWNEES
HEMKHKDEFGVFSITLAPLENGDFAIPHDSKIKVMFVLPDGSKVYRIPAW
ITRATQPSKETAQKYGPTYEGRFWNPPNSYQFKHQRPKFNLANDSIKIYE
AHIGISSPEPKVASYKEFTQNVLPRIKHLGYDAIQLMAIMEHAYYASFGY
QVTNFFAISSRYGTPEDLKELIDTAHSMGILVLLDVIHSHASKNSEDGLN
MFDGSDHQYFHSLTSGRGEHPLWDSRLFNYGSFEVQRFLLANLAYYIDVY
QFDGFRFDGVTSMLYLHHGVGVDHEALAYLMLANDLVHDLLPESAVTIAE
DVSGYPTLCLPRTAGGGGFDYRLAMALPDMWIKLLKTKQDDDWDMGHIVH
TLTNRRHGEKVVAYCESHDQALVGDKTLAFWLMDAAMYTDMTVLKEPTLV
IDRGIALHKMIRLITHSLGGEAYLNFEGNEFGHPEWLDFPRVGNNDSYHY
ARRQFNLVDDDLLRYRHLNEFDAAMQNCESKHQWLNTPQAYVSLKHEVDK
VIAFERNGHLFVFNFHPTQSFTDYRIGVDVAGTYKIVLNTDRAEFGGHNR
IDEAQEFFTTDLEWNNRRNFIQVYIPSRTAIVLTRQM
Ligand information
Ligand IDGLC
InChIInChI=1S/C6H12O6/c7-1-2-3(8)4(9)5(10)6(11)12-2/h2-11H,1H2/t2-,3-,4+,5-,6+/m1/s1
InChIKeyWQZGKKKJIJFFOK-DVKNGEFBSA-N
SMILES
SoftwareSMILES
OpenEye OEToolkits 1.5.0C(C1C(C(C(C(O1)O)O)O)O)O
OpenEye OEToolkits 1.5.0C([C@@H]1[C@H]([C@@H]([C@H]([C@H](O1)O)O)O)O)O
CACTVS 3.341OC[CH]1O[CH](O)[CH](O)[CH](O)[CH]1O
CACTVS 3.341OC[C@H]1O[C@H](O)[C@H](O)[C@@H](O)[C@@H]1O
ACDLabs 10.04OC1C(O)C(OC(O)C1O)CO
FormulaC6 H12 O6
Namealpha-D-glucopyranose;
alpha-D-glucose;
D-glucose;
glucose
ChEMBLCHEMBL423707
DrugBank
ZINCZINC000003861213
PDB chain7p43 Chain C Residue 2 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

[Spin on] [Spin off] [Reset]
[High quality] [Low quality]
[White background] [Black background]
[Spin on] [Spin off] [Reset]
[High quality] [Low quality]
[White background] [Black background]
PDB7p43 The Candida glabrata glycogen branching enzyme structure reveals unique features of branching enzymes of the Saccharomycetaceae phylum.
Resolution1.93 Å
Binding residue
(original residue number in PDB)		W96 K133 Y145
Binding residue
(residue number reindexed from 1)		W96 K133 Y145
Annotation score1
Enzymatic activity
Enzyme Commision number 2.4.1.18: 1,4-alpha-glucan branching enzyme.
Gene Ontology
Molecular Function
GO:0003824 catalytic activity
GO:0003844 1,4-alpha-glucan branching enzyme activity
GO:0004553 hydrolase activity, hydrolyzing O-glycosyl compounds
GO:0008466 glycogenin glucosyltransferase activity
GO:0016757 glycosyltransferase activity
GO:0043169 cation binding
Biological Process
GO:0005975 carbohydrate metabolic process
GO:0005978 glycogen biosynthetic process
Cellular Component
GO:0005737 cytoplasm
GO:0062040 fungal biofilm matrix

View graph for
Molecular Function
View graph for
Biological Process
View graph for
Cellular Component
External links
PDB RCSB:7p43, PDBe:7p43, PDBj:7p43
PDBsum7p43
PubMed34939121
UniProtQ6FJV0|GLGB_CANGA 1,4-alpha-glucan-branching enzyme (Gene Name=GLC3)

[Back to BioLiP]