Structure of PDB 7oyh Chain A Binding Site BS01

Receptor Information
>7oyh Chain A (length=471) Species: 28049 (Acidothermus cellulolyticus) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
MHRVMGIETEYGISVPHQPNANAMAASSQVVNAYAARWDFEGLANVILTN
GARLYVDHAHPEYSTPEVTNPRDAVLWDKAGERIMAEAARRAADLPMGWT
IQLYKNNTDNKGASYGCHENYLMNRSTPFADIVRHLIPFFVTRQVFCGAG
RVGIGADGRGEGFQLSQRADFFEVEVGLETTLKRPIINTRDEPHADPEKY
RRLHVIIGDANMSEIATYLKLGTTALVLAMIEDGFLSQDFSVESPVGALR
AVSHDPTLRYQLRLHDGRRLTAVQLQMEYLEQARKYVEDRFGTDVDDMTR
DVLDRWETTLVRLADDPMQLSRDLDWVAKLSILEGYRQRENLPWSAHKLQ
LVDLQYHDVRPDRGLYNRLVARGRMNLLVDEAAVRTAMHEPPNDTRAYFR
GRCLAKFGAEIAAASWDSVIFDLPGRDSLQRVPTLEPLRGTRAHVGDLLD
RCRSATELVAALTGGENLYFQ
Ligand information
>7oyh Chain B (length=28) Species: 28049 (Acidothermus cellulolyticus) [Search peptide sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
DAILDEIDDVLEENAEEFVRSYIQKGGE
Receptor-Ligand Complex Structure
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PDB7oyh Structures of prokaryotic ubiquitin-like protein Pup in complex with depupylase Dop reveal the mechanism of catalytic phosphate formation.
Resolution1.75 Å
Binding residue
(original residue number in PDB)		E10 G12 I13 H95 H97 Y141 D146 K148 S151 Y152 G153 H155 R205 T217 T218 R221 G372 Y373 R376 H384 K385 L388 Q392 R400 L402 R405 R409
Binding residue
(residue number reindexed from 1)		E10 G12 I13 H58 H60 Y104 D109 K111 S114 Y115 G116 H118 R168 T180 T181 R184 G335 Y336 R339 H347 K348 L351 Q355 R363 L365 R368 R372
Enzymatic activity
Enzyme Commision number 3.4.-.-
Gene Ontology
Molecular Function
GO:0005524 ATP binding
GO:0008233 peptidase activity
GO:0016787 hydrolase activity
GO:0016811 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides
GO:0046872 metal ion binding
Biological Process
GO:0010498 proteasomal protein catabolic process
GO:0019941 modification-dependent protein catabolic process
GO:0070490 protein pupylation

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Molecular Function
View graph for
Biological Process
External links
PDB RCSB:7oyh, PDBe:7oyh, PDBj:7oyh
PDBsum7oyh
PubMed34789727
UniProtA0LU48|DOP_ACIC1 Depupylase (Gene Name=dop)

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