Structure of PDB 7owp Chain A Binding Site BS01

Receptor Information
>7owp Chain A (length=394) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
QGPAKTMEEASKRSYQFWDTQPVPKLGEVVNTHGPVEPDKDNIRQEPYTL
PQGFTWDALDLGDRGVLKELYTLLNENYVEDDDNMFRFDYSPEFLLWALR
PPGWLPQWHCGVRVVSSRKLVGFISAIPANIHIYDTEKKMVEINFLCVHK
KLRSKRVAPVLIREITRRVHLEGIFQAVYTAGVVLPKPVGTCRYWHRSLN
PRKLIEVKFSHLSRNMTMQRTMKLYRLPETPKTAGLRPMETKDIPVVHQL
LTRYLKQFHLTPVMSQEEVEHWFYPQENIIDTFVVENANGEVTDFLSFYT
LPSTIMNHPTHKSLKAAYSFYNVHTQTPLLDLMSDALVLAKMKGFDVFNA
LDLMENKTFLEKLKFGIGDGNLQYYLYNWKCPSMGAEKVGLVLQ
Ligand information
Receptor-Ligand Complex Structure
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PDB7owp Structural and Large-scale Analysis Unveil the Intertwined Paths Promoting NMT-catalyzed Lysine and Glycine Myristoylation.
Resolution1.81 Å
Binding residue
(original residue number in PDB)		V181 E182 D183 D185 F188 F190 N246 T282 G284 Y296 H298 F311 S405 I469 G470 D471 G472 N473 L474 Q496
Binding residue
(residue number reindexed from 1)		V79 E80 D81 D83 F86 F88 N144 T180 G182 Y194 H196 F209 S303 I367 G368 D369 G370 N371 L372 Q394
Enzymatic activity
Enzyme Commision number 2.3.1.-
2.3.1.97: glycylpeptide N-tetradecanoyltransferase.
Gene Ontology
Molecular Function
GO:0004379 glycylpeptide N-tetradecanoyltransferase activity
Biological Process
GO:0006499 N-terminal protein myristoylation

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Molecular Function
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Biological Process
External links
PDB RCSB:7owp, PDBe:7owp, PDBj:7owp
PDBsum7owp
PubMed36181773
UniProtP30419|NMT1_HUMAN Glycylpeptide N-tetradecanoyltransferase 1 (Gene Name=NMT1)

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