Structure of PDB 7ow5 Chain A Binding Site BS01
Receptor Information
>7ow5 Chain A (length=275) Species:
9606
(Homo sapiens) [
Search protein sequence
] [
Download receptor structure
] [
Download structure with residue number starting from 1
] [
View receptor structure
]
SHSMRYFYTSVSRPGRGEPRFIAVGYVDDTQFVRFDSDAASQRMEPRAPW
IEQEGPEYWDQETRNVKAQSQTDRVDLGTLRGYYNQSEDGSHTIQIMYGC
DVGPDGRFLRGYRQDAYDGKDYIALNEDLRSWTAADMAAQITKRKWEAAH
AAEQQRAYLEGRCVEWLRRYLENGKETLQRTDPPKTHMTHHPISDHEATL
RCWALGFYPAEITLTWQRDGEDQTQDTELVETRPAGDGTFQKWAAVVVPS
GEEQRYTCHVQHEGLPKPLTLRWEP
Ligand information
>7ow5 Chain C (length=10) Species:
9606
(Homo sapiens) [
Search peptide sequence
] [
Download ligand structure
] [
Download structure with residue number starting from 1
] [
View ligand structure
]
VVVGAGGVGK
Receptor-Ligand Complex Structure
Global view
Local view
Structure summary
[
Spin on
] [
Spin off
] [
Reset
]
[
High quality
] [
Low quality
]
[
White background
] [
Black background
]
[
Spin on
] [
Spin off
] [
Reset
]
[
High quality
] [
Low quality
]
[
White background
] [
Black background
]
PDB
7ow5
Therapeutic high affinity T cell receptor targeting a KRASG12D cancer neoantigen
Resolution
2.58 Å
Binding residue
(original residue number in PDB)
Y7 Y9 E63 A69 D77 Y84 Y99 D116 T143 K146 W147 A150 Q155 Y159 R163 W167 Y171
Binding residue
(residue number reindexed from 1)
Y6 Y8 E62 A68 D76 Y83 Y98 D115 T142 K145 W146 A149 Q154 Y158 R162 W166 Y170
Enzymatic activity
Enzyme Commision number
?
External links
PDB
RCSB:7ow5
,
PDBe:7ow5
,
PDBj:7ow5
PDBsum
7ow5
PubMed
UniProt
A0A583ZB34
[
Back to BioLiP
]
