Structure of PDB 7ow3 Chain A Binding Site BS01
Receptor Information
>7ow3 Chain A (length=274) Species:
9606
(Homo sapiens) [
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SHSMRYFYTSVSRPGRGEPRFIAVGYVDDTQFVRFDSDAASQRMEPRAPW
IEQEGPEYWDQETRNVKAQSQTDRVDLGTLRGYYNQSEDGSHTIQIMYGC
DVGPDGRFLRGYRQDAYDGKDYIALNEDLRSWTAADMAAQITKRKWEAAH
AAEQQRAYLEGRCVEWLRRYLENGKETLQRTDPPKTHMTHHPISDHEATL
RCWALGFYPAEITLTWQRDGEDQTQDTELVETRPAGDGTFQKWAAVVVPS
GEEQRYTCHVQHEGLPKPLTLRWE
Ligand information
>7ow3 Chain C (length=10) Species:
9606
(Homo sapiens) [
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VVVGAGGVGK
Receptor-Ligand Complex Structure
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PDB
7ow3
Therapeutic high affinity T cell receptor targeting a KRASG12D cancer neoantigen
Resolution
2.46 Å
Binding residue
(original residue number in PDB)
M5 Y7 Y9 E63 N66 D77 Y84 Y99 D116 T143 W147 Y159 R163 W167 Y171
Binding residue
(residue number reindexed from 1)
M4 Y6 Y8 E62 N65 D76 Y83 Y98 D115 T142 W146 Y158 R162 W166 Y170
Enzymatic activity
Enzyme Commision number
?
External links
PDB
RCSB:7ow3
,
PDBe:7ow3
,
PDBj:7ow3
PDBsum
7ow3
PubMed
UniProt
A0A583ZB34
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