Structure of PDB 7orn Chain A Binding Site BS01 |
| >7orn Chain A (length=1700)
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MDYQEYQQFLARINTARDACVAKDIDVDLLMARKDYFGRELCKSLNIEYR
NDVPFIDIILDIRPEVDPLTIDAPHITPDNYLYINNVLYIIDYKVSVSNE
SSVITYDKYYELTRDISDRLSIPIEIVIIRIDPVSRDLHINSDRFKELYP
TIVVDINFNQFFDLKQLLYEKFGDDEEFLLKVAHGDFTLTAPWCKTGCPE
FWKHPIYKEFKMSMPVPERRLFEESVKFNAYESERWNTNLVKIREYTKKD
YSEHISKSAKNIFLASGFYKQPNKNEISEGWTLMVERVQDQREISKSLHD
QKPSIHFIWGAHNPGNSNNATFKLILLSKSLQSIKGISTYTEAFKSLGKM
MDIGDKAIEYEEFCMSLKSKLEPKQINNALVLWEQQFMINNDLIDKSEKL
KLFKNFCGIGKHKQFKNKMLEDLEVSKPKILDFDDANMYLASLTMMEQSK
KILSKSNGLKPDNFILNEFGSRIKDANKETYDNMHKIFETGYWQCISDFS
TLMKNILSVSQYNRHNTFRIAMCANNNVFAIVFPSADIKTKKATVVYSII
VLHKEEENIFNPGCLHGTFKCMNGYISISRAIRLDKERCQRIVSSPGLFL
TTCLLFKHDNPTLVMSDIMNFSIYTSLSITKSVLSLTEPARYMIMNSLAI
SSNVKDYIAEKFSPYTKTLFSVYMTRLIKNACFDAYDQRQRVQLRDIYLS
DYDITQKGIKDNRELTSIWFPGSVTLKEYLTQIYLPFYFNAKGLHEKHHV
MVDLAKTILEIECEQRENIKEIWSTNCTKQTVNLKILIHSLCKNLLADTS
RHNHLRNRIENRNNFRRSITTISTFTSSKSCLKIGDFRKEKELRKMRLAN
PMFVTDEQVCLEVGHCNYEMLRNAMPNYTDYISTKVFDRLYELLDKKVLT
DKPVIEQIMDMMIDHKKFYFTFFNKGQKTSKDREIFVGEYEAKMCMYAVE
RIAKERCKLNPDEMISEPGDGKLKVLEQKSEQEIRFLVETTRQKNREIGK
AKGLKMEINADMSKWSAQDVFYKYFWLIALDPILYPQEKERILYFMCNYM
DKELILPDELLFNLLDQKVAYQNDIIATMTNQLNSNTVLIKRNWLQGNFN
YTSSYVHSCAMSVYKEILKEAITLLDGSILVNSLVHSDDNQTSITIVQDK
MENDKIIDFAMKEFERACLTFGCQANMKKTYVTNCIKEFVSLFNLYGEPF
SIYGRFLLTSVGDCAYIGPYEDLASRISSAQTAIKHGCPPSLAWVSIAIS
HWMTSLTYNMLPGQSNDPIDYFPAENRKDIPIELNGVLDAPLSMISTVGL
ESGNLYFLIKLLSKYTPVMQKRESVVNQIAEVKNWKVEDLTDNEIFRLKI
LRYLVLDAEMDPSDIMGETSDMRGRSILTPRKFTTAGSLRKLYSFSKYQD
RLSSPGGMVELFTYLLEKPELLVTKGEDMKDYMESVIFRYNSKRFKESLS
IQNPAQLFIEQILFSHKPVIDFSGIRDKKEPDILGKVTFTEAYRLLMRDL
SSLELTNDDIQVIYSYIILNDPMMITIANTHILSIYGSPQRRMGMSCSTM
PEFRNLKLIHHSPALVLRAYSKNNPDIQGADPTEMARDLVHLKEFVENTN
LEEKMKVRIAMNEAEKGQRDIVFELKEMTRFYQVCYEYVKSTEHKIKVFI
LPAKSYTTTDFCSLMQGNLIKDKEWYTVHYLKQILEGEAIHSTPIFNIYY |
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| PDB | 7orn Structural snapshots of La Crosse virus polymerase reveal the mechanisms underlying Peribunyaviridae replication and transcription. |
| Resolution | 2.8 Å |
Binding residue
(original residue number in PDB) | Q291 R292 K302 H306 C419 G420 H424 Q426 K430 L435 S438 K439 P440 A548 R592 A593 R595 R600 T642 K643 Y677 K679 E758 H760 H761 V764 K768 R869 Q1116 V1118 Y1120 D1123 |
Binding residue
(residue number reindexed from 1) | Q291 R292 K302 H306 C407 G408 H412 Q414 K418 L423 S426 K427 P428 A536 R580 A581 R583 R588 T630 K631 Y665 K667 E746 H748 H749 V752 K756 R844 Q1067 V1069 Y1071 D1074 |
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