Structure of PDB 7ork Chain A Binding Site BS01 |
| >7ork Chain A (length=2182) Species: 11577 (La Crosse virus)
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MDYQEYQQFLARINTARDACVAKDIDVDLLMARKDYFGRELCKSLNIEYR
NDVPFIDIILDIRPEVDPLTIDAPHITPDNYLYINNVLYIIDYKVSVSNE
SSVITYDKYYELTRDISDRLSIPIEIVIIRIDPVSRDLHINSDRFKELYP
TIVVDINFNQFFDLKQLLYEKFGDDEEFLLKVAHGDFTLTAPWCKTGCPE
FWKHPIYKEFKMSMPVPERRLFEESVKFNAYESERWNTNLVKIREYTKKD
YSEHISKSAKNIFLASGFYKQPNKNEISEGWTLMVERVQDQREISKSLHD
QKPSIHFIWGAHNPGNSNNATFKLILLSKSLQSIKGISTYTEAFKSLGKM
MDIGDKAIEYEEFCMSLKSKALEPKQINNALVLWEQQFMINNDLIDKSEK
LKLFKNFCGIGKHKQFKNKMLEDLEVSKPKILDFDDANMYLASLTMMEQS
KKILSKSNGLKPDNFILNEFGSRIKDANKETYDNMHKIFETGYWQCISDF
STLMKNILSVSQYNRHNTFRIAMCANNNVFAIVFPSADIKTKKATVVYSI
IVLHKEEENIFNPGCLHGTFKCMNGYISISRAIRLDKERCQRIVSSPGLF
LTTCLLFKHDNPTLVMSDIMNFSIYTSLSITKSVLSLTEPARYMIMNSLA
ISSNVKDYIAEKFSPYTKTLFSVYMTRLIKNACFDAYDQRQRVQLRDIYL
SDYDITQKGIKDNRELTSIWFPGSVTLKEYLTQIYLPFYFNAKGLHEKHH
VMVDLAKTILEIECEQRENIKEIWSTNCTKQTVNLKILIHSLCKNLLADT
SRHNHLRNRIENRNNFRRSITTISTFTSSKSCLKIGDFRKEKELRKMRLA
NPMFVTDEQVCLEVGHCNYEMLRNAMPNYTDYISTKVFDRLYELLDKKVL
TDKPVIEQIMDMMIDHKKFYFTFFNKGQKTSKDREIFVGEYEAKMCMYAV
ERIAKERCKLNPDEMISEPGDGKLKVLEQKSEQEIRFLVETTRQKNREID
EAIEALATLGKIEKLSLGKAKGLKMEINADMSKWSAQDVFYKYFWLIALD
PILYPQEKERILYFMCNYMDKELILPDELLFNLLDQKVAYQNDIIATMTN
QLNSNTVLIKRNWLQGNFNYTSSYVHSCAMSVYKEILKEAITLLDGSILV
NSLVHSDDNQTSITIVQDKMENDKIIDFAMKEFERACLTFGCQANMKKTY
VTNCIKEFVSLFNLYGEPFSIYGRFLLTSVGDCAYIGPYEDLASRISSAQ
TAIKHGCPPSLAWVSIAISHWMTSLTYNMLPGQSNDPIDYFPAENRKDIP
IELNGVLDAPLSMISTVGLESGNLYFLIKLLSKYTPVMQKRESVVNQIAE
VKNWKVEDLTDNEIFRLKILRYLVLDAEMDPSDIMGETSDMRGRSILTPR
KFTTAGSLRKLYSFSKYQDRLSSPGGMVELFTYLLEKPELLVTKGEDMKD
YMESVIFRYNSKRFKESLSIQNPAQLFIEQILFSHKPVIDFSGIRDKKEP
DILGKVTFTEAYRLLMRDLSSLELTNDDIQVIYSYIILNDPMMITIANTH
ILSIYGSPQRRMGMSCSTMPEFRNLKLIHHSPALVLRAYSKNNPDIQGAD
PTEMARDLVHLKEFVENTNLEEKMKVRIAMNEAEKGQRDIVFELKEMTRF
YQVCYEYVKSTEHKIKVFILPAKSYTTTDFCSLMQGNLIKDKEWYTVHYL
KQILSGGHKAIMQHNATSEQNIAFECFKLITHFADSFIDSLSRSAFLQLI
IDEFSYKDVKVSKLYDIIKNGYNRTDFIPLLFRTGDLRQADLDKYDAMKS
HERVTWNDWQTSRHLDMGSINLTITGYNRSITIIGEDNKLTYAELCLTRK
TPENITISGRKLLGSRHGLKFENMSKIQTYPGNYYITYRKKDRHQFVYQI
HSHESITRRNEEHMAIIYNEITPVCVVNVAEVDGDQRILIRSLDYLNNDI
FSLSRIKVGLDEFATIKKAHFSKMVSFEGPPIKTGLLDLTELMKSQDLLN
LNYDNIRNSNLISFSKLICCEGSDNINDGLEFLSDDPMNFTEGEAIHSTP
IFNIYYSKRGERHMTYRNAIKLLIERETKIFEEAFTFSENGFISPENLGC
LEAVVSLIKLLKTNEWSTVIDKCIHICLIKNGMDHMYHSFDVPINWVMFR
EFINSLPGTDIPPWNVMTENFKKKCIALINSK |
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| PDB | 7ork Structural snapshots of La Crosse virus polymerase reveal the mechanisms underlying Peribunyaviridae replication and transcription. |
| Resolution | 3.1 Å |
Binding residue
(original residue number in PDB) | Q291 R292 K302 H306 C419 G420 G422 H424 Q426 K430 L435 K439 P440 A548 R592 A593 R595 R600 T642 K643 Y677 K679 E758 H760 H761 V764 K768 H890 Q1116 V1118 Y1120 D1123 |
Binding residue
(residue number reindexed from 1) | Q291 R292 K302 H306 C408 G409 G411 H413 Q415 K419 L424 K428 P429 A537 R581 A582 R584 R589 T631 K632 Y666 K668 E747 H749 H750 V753 K757 H866 Q1086 V1088 Y1090 D1093 |
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