Structure of PDB 7op2 Chain A Binding Site BS01

Receptor Information
>7op2 Chain A (length=187) Species: 1123958 (Chimpanzee adenovirus Y25) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
KLTLWTTPDPSPNCQLLSDRDAKFTLCLTKCGSQILGTVAVAAVTVGSAL
NPINDTVKSAIVFLRFDSDGVLMSNSSMVGDYWNFREGQTTQSVAYTNAV
GFMPNLGAYPKTQSKTPKNSIVSQVYLNGETTMPMTLTITFNGTDEKDTT
PVSTYSMTFTWQWTGDYKDKNITFATNSFTFSYMAQE
Ligand information
Ligand IDCA
InChIInChI=1S/Ca/q+2
InChIKeyBHPQYMZQTOCNFJ-UHFFFAOYSA-N
SMILES
SoftwareSMILES
CACTVS 3.341[Ca++]
ACDLabs 10.04
OpenEye OEToolkits 1.5.0		[Ca+2]
FormulaCa
NameCALCIUM ION
ChEMBL
DrugBankDB14577
ZINC
PDB chain7op2 Chain A Residue 401 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
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PDB7op2 ChAdOx1 interacts with CAR and PF4 with implications for thrombosis with thrombocytopenia syndrome.
Resolution1.59 Å
Binding residue
(original residue number in PDB)		E331 D333
Binding residue
(residue number reindexed from 1)		E146 D148
Annotation score4
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Biological Process
GO:0019062 virion attachment to host cell
Cellular Component
GO:0019028 viral capsid

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Biological Process
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Cellular Component
External links
PDB RCSB:7op2, PDBe:7op2, PDBj:7op2
PDBsum7op2
PubMed34851659
UniProtG9G864

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