Structure of PDB 7oml Chain A Binding Site BS01

Receptor Information
>7oml Chain A (length=445) Species: 224308 (Bacillus subtilis subsp. subtilis str. 168) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
GKYFGTDGVRGVANSELTPELAFKVGRFGGYVLTKDKQRPKVLIGRDTRI
SGHMLEGALVAGLLSIGAEVMRLGVISTPGVSYLTKAMDAEAGVMISASH
NPVQDNGIKFFGGDGFKLSDEQEAEIERLMDEPEDKLPRPVGADLGLVND
YFEGGQKYLQFLKQTADEDFTGIHVALDCANGATSSLATHLFADLDADVS
TMGTSPNGLNINDGVGSTHPEALSAFVKEKNADLGLAFDGDGDRLIAVDE
KGNIVDGDQIMYICSKHLKSEGRLKDDTVVSTVMSNLGFYKALEKEGIKS
VQTAVGDRYVVEAMKKDGYNVGGEQSGHLIFLDYNTTGDGLLSAIMLMNT
LKATGKPLSELAAEMQKFPQLLVNVRVTDKYKVEENEKVKAVISEVEKEM
NGDGRILVRPSGTEPLVRVMAEAKTKELCDEYVNRIVEVVRSEMG
Ligand information
Ligand IDMG
InChIInChI=1S/Mg/q+2
InChIKeyJLVVSXFLKOJNIY-UHFFFAOYSA-N
SMILES
SoftwareSMILES
ACDLabs 10.04
OpenEye OEToolkits 1.5.0		[Mg+2]
CACTVS 3.341[Mg++]
FormulaMg
NameMAGNESIUM ION
ChEMBL
DrugBankDB01378
ZINC
PDB chain7oml Chain A Residue 501 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
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PDB7oml Structural basis for the inhibition of the Bacillus subtilis c-di-AMP cyclase CdaA by the phosphoglucomutase GlmM.
Resolution2.9 Å
Binding residue
(original residue number in PDB)		S100 D240 D242 D244
Binding residue
(residue number reindexed from 1)		S99 D239 D241 D243
Annotation score1
Enzymatic activity
Enzyme Commision number 5.4.2.10: phosphoglucosamine mutase.
Gene Ontology
Molecular Function
GO:0000287 magnesium ion binding
GO:0004615 phosphomannomutase activity
GO:0008966 phosphoglucosamine mutase activity
GO:0016853 isomerase activity
GO:0016868 intramolecular phosphotransferase activity
GO:0046872 metal ion binding
Biological Process
GO:0005975 carbohydrate metabolic process
GO:0006048 UDP-N-acetylglucosamine biosynthetic process
GO:0009252 peptidoglycan biosynthetic process
Cellular Component
GO:0005829 cytosol

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:7oml, PDBe:7oml, PDBj:7oml
PDBsum7oml
PubMed34678313
UniProtO34824|GLMM_BACSU Phosphoglucosamine mutase (Gene Name=glmM)

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