Structure of PDB 7om3 Chain A Binding Site BS01

Receptor Information
>7om3 Chain A (length=759) Species: 69014 (Thermococcus kodakarensis KOD1) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
MILDTDYITEDGKPVIRIFKKENGEFKIEYDRTFEPYFYALLKDDSAIEE
VKKITAERHGTVVTVKRVEKVQKKFLGRPVEVWKLYFTHPQDVPAIRDKI
REHPAVIDIYEYDIPFAKRYLIDKGLVPMEGDEELKMLAFAIATLYHEGE
EFAEGPILMISYADEEGARVITWKNVDLPYVDVVSTEREMIKRFLRVVKE
KDPDVLITYNGDNFDFAYLKKRCEKLGINFALGRDGSEPKIQRMGDRFAV
EVKGRIHFDLYPVIRRTINLPTYTLEAVYEAVFGQPKEKVYAEEITTAWE
TGENLERVARYSMEDAKVTYELGKEFLPMEAQLSRLIGQSLWDVSRSSTG
NLVEWFLLRKAYERNELAPNKPDEKELARRRQSYEGGYVKEPERGLWENI
VYLDFRSLYPSIIITHNVSPDTLNREGCKEYDVAPQVGHRFCKDFPGFIP
SLLGDLLEERQKIKKKMKATIDPIERKLLDYRQRAIKILANSYYGYYGYA
RARWYCKECAESVTAWGREYITMTIKEIEEKYGFKVIYSDTDGFFATIPG
ADAETVKKKAMEFLKYINAKLPGALELEYEGFYKRGFFVTKKKYAVIDEE
GKITTRGLEIVRRDWSEIAKETQARVLEALLKDGDVEKAVRIVKEVTEKL
SKYEVPPEKLVIHEQITRDLKDYKATGPHVAVAKRLAARGVKIRPGTVIS
YIVLKGSGRIGDRAIPFDEFDPTKHKYDAEYYIENQVLPAVERILRAFGY
RKEDLRYQK
Ligand information
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB7om3 Structural Basis for The Recognition of Deaminated Nucleobases by An Archaeal DNA Polymerase.
Resolution1.92 Å
Binding residue
(original residue number in PDB)
Y7 P36 Y37 R58 H59 H89 P90 Q91 V93 P94 R97 Y112 D113 I114 P115 F116 K118 R119 K240 G245 R247 D343 S348 T349 N351 K371 S383 Y384 G386 G387 V389 S492 G495 Y496 G498 Y499 R501 T590 K591 K593 W615 P678 R709 I710 G711 Y731 R743
Binding residue
(residue number reindexed from 1)
Y7 P36 Y37 R58 H59 H89 P90 Q91 V93 P94 R97 Y112 D113 I114 P115 F116 K118 R119 K240 G245 R247 D343 S348 T349 N351 K371 S383 Y384 G386 G387 V389 S492 G495 Y496 G498 Y499 R501 T590 K591 K593 W615 P678 R709 I710 G711 Y731 R743
Enzymatic activity
Enzyme Commision number 2.7.7.7: DNA-directed DNA polymerase.
3.1.-.-
Gene Ontology
Molecular Function
GO:0000166 nucleotide binding
GO:0003676 nucleic acid binding
GO:0003677 DNA binding
GO:0003887 DNA-directed DNA polymerase activity

View graph for
Molecular Function
External links
PDB RCSB:7om3, PDBe:7om3, PDBj:7om3
PDBsum7om3
PubMed34486208
UniProtP77933|DPOL_THEKO DNA polymerase (Gene Name=pol)

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