Structure of PDB 7ogk Chain A Binding Site BS01

Receptor Information
>7ogk Chain A (length=695) Species: 83333 (Escherichia coli K-12) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
MLNPIVRKFQYGQHTVTLETGMMARQATAAVMVSMDDTAVFVTVVGQKKA
KPGQDFFPLTVNYQERTYAAGRIPGSFFRREGRPSEGETLIARLIDRPIR
PLFPEGFVNEVQVIATVVSVNPQVNPDIVAMIGASAALSLSGIPFNGPIG
AARVGYINDQYVLNPTQDELKESKLDLVVAGTEAAVLMVESEAQLLSEDQ
MLGAVVFGHEQQQVVIQNINELVKEAGKPRWDWQPEPVNEALNARVAALA
EARLSDAYRITDKQERYAQVDVIKSETIATLLAEDETLDENELGEILHAI
EKNVVRSRVLAGEPRIDGREKDMIRGLDVRTGVLPRTHGSALFTRGETQA
LVTATLGTARDAQVLDELMGERTDTFLFHYNFPPYSVGETGMVGSPKRRE
IGHGRLAKRGVLAVMPDMDKFPYTVRVVSEITESNGSSSMASVCGASLAL
MDAGVPIKAAVAGIAMGLVKEGDNYVVLSDILGDEDHLGDMDFKVAGSRD
GISALQMDIKIEGITKEIMQVALNQAKGARLHILGVMEQAINAPRGDISE
FAPRIHTIKINPDKIKDVIGKGGSVIRALTEETGTTIEIEDDGTVKIAAT
DGEKAKHAIRRIEEITAEIEVGRVYTGKVTRIVDFGAFVAIGGGKEGLVH
ISQIADKRVEKVTDYLQMGQEVPVKVLEVDRQGRIRLSIKEATEQ
Ligand information
Receptor-Ligand Complex Structure
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PDB7ogk A cooperative PNPase-Hfq-RNA carrier complex facilitates bacterial riboregulation.
Resolution3.4 Å
Binding residue
(original residue number in PDB)
G75 F77 D366 G572 G573
Binding residue
(residue number reindexed from 1)
G75 F77 D366 G572 G573
Enzymatic activity
Enzyme Commision number 2.7.7.8: polyribonucleotide nucleotidyltransferase.
Gene Ontology
Molecular Function
GO:0000175 3'-5'-RNA exonuclease activity
GO:0000287 magnesium ion binding
GO:0003676 nucleic acid binding
GO:0003723 RNA binding
GO:0004654 polyribonucleotide nucleotidyltransferase activity
GO:0005515 protein binding
GO:0016779 nucleotidyltransferase activity
GO:0035438 cyclic-di-GMP binding
GO:0042802 identical protein binding
GO:0046872 metal ion binding
Biological Process
GO:0006396 RNA processing
GO:0006401 RNA catabolic process
GO:0006402 mRNA catabolic process
GO:0009408 response to heat
Cellular Component
GO:0005737 cytoplasm
GO:0005829 cytosol
GO:0016020 membrane
GO:1990061 bacterial degradosome

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Molecular Function

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Biological Process

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Cellular Component
External links
PDB RCSB:7ogk, PDBe:7ogk, PDBj:7ogk
PDBsum7ogk
PubMed34157309
UniProtP05055|PNP_ECOLI Polyribonucleotide nucleotidyltransferase (Gene Name=pnp)

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